An electron microscopic study on stellate cells in the rabbit adenohypophysis under various endocrine conditions

An electron microscopic study on stellate cells in the rabbit adenohypophysis under various endocrine conditions
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不同内分泌条件下兔腺垂体星状细胞的电镜研究

DOI:
10.1007/bf00234784
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发表时间:
2004
影响因子:
3.6
通讯作者:
Y. Shiotani
Y. Shiotani
中科院分区:
生物学3区
文献类型:
--
作者:
Y. Shiotani

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在正常和实验条件下,如哺乳、甲状腺切除、肾上腺切除或去势,用电子显微镜观察了兔腺垂体中的星状细胞。在对照动物中,星状细胞在细胞核周围有稀少的细胞质,并有细长的突起延伸到颗粒细胞之间。这些突起通过桥粒相互连接,形成一个网络。细胞质内有丰富的微丝和发育不良的普通细胞器,但缺乏分泌颗粒。在腺垂体中,颗粒细胞发生了特征性的变化,星状细胞也出现了明显的形态变化,各组相似。总体而言,它们变得肥大,并含有发达的高尔基体和表面粗糙的内质网。常见溶酶体或脂滴。在相邻的星状细胞之间,细胞间管明显发达,可见大量微绒毛。以上结果表明,星状细胞不仅是支持细胞,而且在腺垂体的功能中起着重要的作用,如为颗粒细胞提供物质或废物的处理。
Stellate cells in the rabbit adenohypophysis were observed electron microscopically under normal and experimental conditions such as lactation, thyroidectomy, adrenalectomy, or castration. In control animals stellate cells had a scanty cytoplasm surrounding the nucleus and possessed slender processes extending between granulated cells. The processes were interconnected by desmosomes to form a meshwork. In the cytoplasm, abundant microfilaments were present as well as ill-developed ordinary cell organelles, but secretory granules were absent. In the adenohypophysis of experimental groups, in which the granulated cells underwent characteristic changes, stellate cells also showed remarkable morphological alterations which were similar in all groups. In general, they became hypertrophied, and contained a well-developed Golgi apparatus and rough-surfaced endoplasmic reticulum. Lysosomes or lipid droplets were frequently encountered. Between adjacent stellate cells, intercellular canals were markedly developed and many microvilli were noticed. Based on the above data, it is suggested that the stellate cells are not only sustentacular elements, but play an important role in the function of the adenohypophysis, such as the supply of materials to granulated cells or the disposal of waste products.
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者:
Yamamoto I;Nakao N;Kaiya H;Miyazato M;Tsushima N;Arai T;Tanaka M;大砂まるみ・加藤幸雄
通讯作者: 大砂まるみ・加藤幸雄