The clinical diagnosis of Alzheimer's disease.
The clinical diagnosis of Alzheimer's disease.
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DOI：
10.1001/archneur.1987.00520130016010
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发表时间：
1987
影响因子：
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通讯作者：
J. Wade;T. Mirsen;V. Hachinski;M. Fisman;C. Lau;H. Merskey
中科院分区：
文献类型：
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作者：
J. Wade;T. Mirsen;V. Hachinski;M. Fisman;C. Lau;H. Merskey
比较了65名患有痴呆症并在一生中接受过纵向研究的患者的临床和病理诊断。在没有其他诊断的情况下，诊断Alzheimer型痴呆（DAT）的敏感性为87%，特异性为78%。缺血量表评分不能很好地区分单纯多梗死性痴呆患者和DAT和多梗死性痴呆患者。然而，38例单纯DAT中有35例缺血评分为4分或更低。
Clinical and pathologic diagnoses are compared in 65 patients who had dementia and who had been studied longitudinally during life. The sensitivity of diagnosis for dementia of the Alzheimer type (DAT) without any other diagnosis was 87%, and the specificity was 78%. The ischemic scale score did not discriminate well between patients with pure multi-infarct dementia and those with both DAT and multi-infarct dementia. However, 35 of 38 cases of pure DAT had a score of 4 or less on the ischemic scale.