Occupational risk factors
Occupational risk factors
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DOI：
10.1080/03008880802284423
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发表时间：
2008-09-01
影响因子：
--
通讯作者：
Lerner, Seth P.
中科院分区：
文献类型：
--
作者：
Delclos, George L.;Lerner, Seth P.
暴露于选定的化学致癌物、职业或行业与膀胱癌之间的关联已得到充分证实，据估计，20-27%的膀胱癌可归因于职业暴露。职业接触引起膀胱癌的风险不仅取决于化合物致癌性、接触强度和工作场所特征，而且还取决于个人对这些癌症的易感性。工业化国家的监管控制已导致工作场所接触膀胱致癌物的负担减轻。不幸的是，在许多发展中国家，情况不太可能如此，因为这些国家的危险技术可能是从较发达国家转让来的，而且这些国家的规章执行和工人保护可能不那么严格。
The association between exposure to selected chemical carcinogens, occupations or industries and bladder cancer is well established, and it is estimated that 20-27% of bladder cancers are attributable to occupational exposures. The risk of bladder cancer stemming from an occupational exposure depends not only on compound carcinogenicity, exposure intensity and workplace characteristics, but also on individual susceptibility to these cancers. Regulatory controls in industrialized nations have resulted in a decreased burden of exposure to bladder carcinogens in the workplace. Unfortunately, the same is unlikely in many developing countries, where risky technologies may have been transferred from more developed countries, and where enforcement of regulations and worker protection are likely to be less stringent.