THE HOLIDAY HEART - ELECTROPHYSIOLOGIC STUDIES OF ALCOHOL EFFECTS IN ALCOHOLICS
THE HOLIDAY HEART - ELECTROPHYSIOLOGIC STUDIES OF ALCOHOL EFFECTS IN ALCOHOLICS
复制标题
DOI：
10.7326/0003-4819-98-2-135
复制
发表时间：
1983-01-01
影响因子：
39.2
通讯作者：
SCHAAL, SF
中科院分区：
文献类型：
--
作者：
GREENSPON, AJ;SCHAAL, SF
尽管假日心脏综合症（以急性酒精摄入后节律紊乱为特征）是众所周知的，但酒精潜在的心律失常作用尚未得到研究。对 14 名有节律紊乱和饮酒史的患者（其中 2 名患有充血性心肌病）进行了电生理学研究。一名患者患有非持续性室性心动过速，一名患者患有非持续性房颤，一名患者出现配对心室反应，其余患者对额外刺激技术没有反应。在饮用 90 毫升 80 度威士忌后，14 名患者中有 10 名出现持续或非持续性房性或室性快速心律失常。饮酒后希氏心室传导显着延长；值得注意的是，一名患者此前曾在急性饮酒后出现 Mobitz 2 房室传导阻滞。对于有长期饮酒史和心脏病史的患者来说，适量饮酒可能会导致节律紊乱。
Although the holiday heart syndrome, highlighted by rhythm disturbances after acute alcohol ingestion, is well known, the potential arrhythmogenic effects of alcohol have not been studied. Fourteen patients (2 with congestive cardiomyopathy) with a history of rhythm disturbances and alcohol consumption were studied electrophysiologically. One patient had nonsustained ventricular tachycardia, 1 had nonsustained atrial fibrillation, 1 had paired ventricular responses and the remainder had no response to the extrastimulus technique. After 90 ml of 80 proof whiskey, 10 of 14 patients developed sustained or nonsustained atrial or ventricular tachyarrhythmias. Significant prolongation of His-ventricular conduction was seen after alcohol intake; this was noteworthy as 1 patient had previously shown Mobitz 2 atrioventricular block after acute alcohol consumption. Alcohol in modest doses had the potential to produce rhythm disturbances in patients with a history of chronic alcohol consumption and heart disease.