Cell volume control in the Plasmodium-infected erythrocyte

Cell volume control in the Plasmodium-infected erythrocyte
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DOI:
10.1016/j.pt.2003.10.015
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发表时间:
2004-01-01
影响因子:
9.6
通讯作者:
Kirk, K
Kirk, K
中科院分区:
医学1区
文献类型:
--
作者:
Allen, RJW;Kirk, K

文献摘要

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当疟原虫在宿主红细胞内生长时,它摄入和消化的血红蛋白远多于为蛋白质合成提供氨基酸所需的血红蛋白。最近的一篇论文重点关注这一过程在限制受感染细胞肿胀程度方面的作用,从而防止宿主红细胞在新一代寄生虫准备逃跑之前裂解。
As the malaria parasite grows within the host erythrocyte, it ingests and digests far more haemoglobin than is required to provide amino acids for protein synthesis. A recent paper focuses attention on the role of this process in limiting the extent of swelling undergone by the infected cell and thereby preventing the host erythrocyte from lysing before the new generation of parasites are ready to make their escape.