A Bioinspired Light-Controlled Ionic Switch Based on Nanopipettes
A Bioinspired Light-Controlled Ionic Switch Based on Nanopipettes
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基于纳米移液器的仿生光控离子开关
DOI：
10.1002/elan.201400661
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发表时间：
2015
期刊：
影响因子：
3
通讯作者：
Mao Lanqun
中科院分区：
文献类型：
--
作者：
Li Ting;He Xiulan;Yu Ping;Mao Lanqun
由于离子器件在分子计算机、生物传感和电子电路等方面的潜在应用，发展新型离子器件的制备原理已引起人们的广泛关注。受光遗传学通过光控蛋白质改变膜电压的启发，这里展示了一种基于纳米移液管的新型光控离子开关。在暴露于可见光时，螺吡喃（SP）不与Zn 2+配位，导致相对大的离子电流。而在紫外光照射下，SP转化为与Zn 2+配位的汞（MC），从而导致离子电流的降低。紫外/维斯光照射可以可逆地调制离子电流。进行有限元模拟以了解基于纳米移液管的光控离子开关的可能机制。
Development of new principles for fabrication of novel ionic devices has attracted much attention due to the potential applications of ionic devices in molecular computer, biosensing and electronic circuit. Inspired by optogenetics altering membrane voltage via light‐controlled proteins, a new kind of light‐controlled ionic switch was demonstrated here based on nanopipettes. Upon exposure to visible light, spiropyran (SP) does not coordinate with Zn2+, resulting in a relatively large ionic current. While, upon UV light irradiation, SP was transformed into merocyanine (MC) that coordinates with Zn2+and thereby results in the decrease in the ionic current. The ionic current could be reversibly modulated by UV/Vis light irradiation. The finite‐element simulation was performed to understand the possible mechanism underlying the light‐controlled ionic switch based on nanopipettes.