Micro-Nanostructured Protein Arrays: A Tool for Geometrically Controlled Ligand Presentation

Micro-Nanostructured Protein Arrays: A Tool for Geometrically Controlled Ligand Presentation
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DOI:
10.1002/smll.200801219
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发表时间:
2009-05-04
期刊:
影响因子:
13.3
通讯作者:
Spatz, Joachim P.
Spatz, Joachim P.
中科院分区:
材料科学1区
文献类型:
--
作者:
Aydin, Daniel;Schwieder, Marco;Spatz, Joachim P.

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一种新的方法,用于快速制造准六边形有序金纳米颗粒阵列(见图)的微米级补丁的扩展区域。由此产生的基板作为模板的蛋白质的位点特异性固定到金纳米粒子,使纳米和显微镜控制的蛋白质沉积。
A novel approach for the rapid fabrication of extended areas of micrometer-scaled patches of quasi-hexagonally ordered gold nanoparticle arrays (see image) is presented. The resulting substrates serve as templates for the site-specific immobilization of proteins to gold nanoparticles enabling nanoscopically and microscopically controlled protein deposition.