Cognitive support at episodic encoding and retrieval:: Similar patterns of utilization in community-based samples of Alzheimer's disease and vascular dementia patients
Cognitive support at episodic encoding and retrieval:: Similar patterns of utilization in community-based samples of Alzheimer's disease and vascular dementia patients
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DOI：
10.1076/jcen.21.6.816.862
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发表时间：
1999-12-01
影响因子：
2.2
通讯作者：
Bäckman, L
中科院分区：
文献类型：
--
作者：
Almkvist, O;Fratiglioni, L;Bäckman, L
本研究探讨了阿尔茨海默病（AD）和血管性痴呆（VaD）在情景记忆模式上的差异这一假说。对AD和VaD痴呆患者和正常老年人进行情景记忆任务评估，包括自由回忆和识别缓慢和快速呈现的无关词以及自由和线索回忆的有组织词。结果显示，两个痴呆组在所有记忆变量上都存在普遍缺陷，尽管AD和VaD患者在所有测量中无法区分。正常的老年人表现出熟练的利用更多的学习时间，组织性和类别线索。相比之下，AD和VaD患者能够受益于认知支持时，只有在编码和检索提供指导。此外，在正常的老年人，回忆无关的话的特点是由一个相对平等的贡献，从初级和二级记忆，而痴呆症患者主要依赖于初级记忆。结果表明，AD和VaD患者之间的相似性方面的情节记忆障碍的性质，尽管疾病之间的病因差异。
The hypothesis that Alzheimer's disease (AD) and vascular dementia (VaD) differ in the pattern of episodic memory was examined in this study. Demented patients with AD and VaD and normal old adults were assessed on episodic memory tasks, including free recall and recognition of slowly and rapidly presented unrelated words and free and cued recall of organizable words. Results showed a general deficit in both demented groups across all memory variables, although the AD and VaD patients were indistinguishable across all measures. The normal old showed proficient utilization of more study time, organizability, and category cues. By contrast, the AD and VaD patients were able to benefit from cognitive support only when guidance was provided at both encoding and retrieval. In addition, in the normal old, recall of unrelated words was characterized by a relatively equal contribution from primary and secondary memory, whereas the demented patients relied predominantly on primary memory. The results suggests a similarity between AD and VaD patients with regard to the nature of the episodic memory impairment, despite etiologic differences between the diseases.