BRAIN-STEM CONTROL OF MASSETERIC REFLEX ACTIVITY DURING SLEEP AND WAKEFULNESS - MEDULLA
BRAIN-STEM CONTROL OF MASSETERIC REFLEX ACTIVITY DURING SLEEP AND WAKEFULNESS - MEDULLA
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DOI：
10.1016/0014-4886(79)90009-8
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发表时间：
1979-01-01
影响因子：
5.3
通讯作者：
WILLS, N
中科院分区：
文献类型：
--
作者：
CHASE, MH;WILLS, N
研究了网状反应逆转现象中延髓前部的可能参与。这种现象发生时，条件刺激，传递到桥中脑网状核心，产生增加咬肌反射兴奋性在清醒和安静的睡眠，但诱导抑制兴奋性在活跃的睡眠。在猫[13]中植入慢性电极，该电极向中脑第5核传递测试刺激以引起咬肌反射，向桥脑延髓连接处的部位施加条件刺激，并在清醒、安静睡眠和主动睡眠期间监测自由移动的猫的EEG、眼电图（EOG）和肌电图（EMG）。在清醒和安静的睡眠，条件刺激可靠地产生反射促进（主要是从中间网站），持续10-40毫秒的峰值效应在20毫秒。在活跃的睡眠，同样的刺激产生反射抑制具有类似的时间过程。从脑桥延髓交界处的网站获得的时间过程模式类似于从喙脑干区域产生的，除了许多延髓网站产生短潜伏期反射抑制整个清醒，安静的睡眠和活跃的睡眠。条件电流诱导的反射促进和抑制的阈值较低，从网站在延髓水平比所需的脑桥或中脑水平。
The possible involvement of the anterior medulla in the phenomenon of reticular response-reversal was studied. This phenomenon occurs when conditioning stimulation, delivered to the pontomesencephalic reticular core, produces an increase in masseteric reflex excitability during wakefulness and quiet sleep, but induces a suppression of excitability during active sleep. Cats [13] were implanted with chronic electrodes which delivered a test stimulus to the mesencephalic 5th nucleus to evoke the masseteric reflex, to apply conditioning stimuli to sites at the pontomedullary junction and to monitor the EEG, electrooculogram (EOG) and electromyogram (EMG) in the freely moving cat during wakefulness, quiet sleep and active sleep. During wakefulness and quiet sleep, conditioning stimulation reliably produced reflex facilitation (principally from medial sites) which lasted 10-40 ms with a peak effect at 20 ms. During active sleep, the same stimulation produced reflex suppression with a similar time course. Time course patterns obtained from sites at the pontomedullary junction resembled those generated from rostral brain stem regions with the exception that many medullary sites yielded short latency reflex suppression throughout wakefulness, quiet sleep and active sleep. Lower thresholds of conditioning current induced reflex facilitation and suppression from sites at the medullary level than were required at the pontine or mesencephalic levels.