Mucosal hyperpigmentation from prophylactic minocycline for EGFR inhibitor

Mucosal hyperpigmentation from prophylactic minocycline for EGFR inhibitor
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EGFR 抑制剂预防性米诺环素引起的粘膜色素沉着过度

DOI:
10.1111/jdv.12978
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发表时间:
2016
期刊:
J Eur Acad Dermatol Venereol
影响因子:
--
通讯作者:
Shimizu H
Shimizu H
中科院分区:
--
文献类型:
--
作者:
Imafuku K;Natsuga K*;Aoyagi S;Shimizu H

文献摘要

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本文讨论了一名58岁男性下咽癌患者的病例,该患者的舌头出现色素沉着。所涵盖的主题包括导致米诺环素诱导的粘膜色素沉着的诊断的检查结果,所有表皮生长因子受体(EGFR)抑制剂与各种皮肤病反应的关联,以及米诺环素诱导的色素沉着的四种临床类型。
The article discusses the case of a 58-year-old male hypopharyngeal carcinoma patient who presented with pigmentation on his tongue. Topics covered include the findings of examinations which led to the diagnosis of minocycline-induced mucosal pigmentation, the association of all epidermal growth factor receptor (EGFR) inhibitors to various dermatologic reactions, and the four clinical types of minocycline-induced pigmentation.