Selective intracellular delivery of perfluorocarbon nanodroplets for cytotoxicity threshold reduction on ultrasound‐induced vaporization
Selective intracellular delivery of perfluorocarbon nanodroplets for cytotoxicity threshold reduction on ultrasound‐induced vaporization
复制标题
DOI：
10.1002/cnr2.1165
复制
发表时间：
2019-08
期刊：
影响因子：
1.7
通讯作者：
A. Ishijima;S. Yamaguchi;T. Azuma;E. Kobayashi;Y. Shibasaki;Teruyuki Nagamune;I. Sakuma
中科院分区：
文献类型：
--
作者：
A. Ishijima;S. Yamaguchi;T. Azuma;E. Kobayashi;Y. Shibasaki;Teruyuki Nagamune;I. Sakuma
相变纳米液滴（PCND）是液体全氟化碳纳米颗粒，作为超声响应纳米医学受到了广泛关注。汽化现象已被用于机械治疗肿瘤。然而，用于诱导汽化的超声压力必须较低，以避免损伤非靶组织。
Phase‐change nanodroplets (PCNDs), which are liquid perfluorocarbon nanoparticles, have garnered much attention as ultrasound‐responsive nanomedicines. The vaporization phenomenon has been employed to treat tumors mechanically. However, the ultrasound pressure applied to induce vaporization must be low to avoid damage to nontarget tissues.