Characterization of synthetic foam structures used to manufacture artificial vertebral trabecular bone
Characterization of synthetic foam structures used to manufacture artificial vertebral trabecular bone
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DOI：
10.1016/j.msec.2017.03.158
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发表时间：
2017-07-01
影响因子：
7.9
通讯作者：
Schrempf, Andreas
中科院分区：
文献类型：
--
作者：
Fuerst, David;Senck, Sascha;Schrempf, Andreas
反映人体骨力学性能的人工材料对于有效和可靠的植入物测试和设计至关重要。它们对于外科手术的真实模拟也是非常有益的。因此，本研究的目的是通过静态压缩测试和微计算机断层扫描来表征两组自行开发的合成泡沫结构。使用两种矿物填料和不同量的发泡剂来产生合成开孔泡沫的不同膨胀行为。因此，所得的压缩和形态测量特性在两组内以及两组之间略有不同。除了结构的各向异性，合成泡沫材料的压缩和形态测量性能被证明反映了人类椎体骨小梁的各自特点，在很好的近似。总之，所产生的人造材料可用于制造用于外科训练的有效合成骨。此外，它们为研究骨小梁微观结构和生物力学性能之间的关系提供了新的可能性。(C)2017 Elsevier B.V.版权所有。
Artificial materials reflecting the mechanical properties of human bone are essential for valid and reliable implant testing and design. They also are of great benefit for realistic simulation of surgical procedures. The objective of this study was therefore to characterize two groups of self-developed synthetic foam structures by static compressive testing and by microcomputed tomography. Two mineral fillers and varying amounts of a blowing agent were used to create different expansion behavior of the synthetic open-cell foams. The resulting compressive and morphometric properties thus differed within and also slightly between both groups. Apart from the structural anisotropy, the compressive and morphometric properties of the synthetic foam materials were shown to mirror the respective characteristics of human vertebral trabecular bone in good approximation. In conclusion, the artificial materials created can be used to manufacture valid synthetic bones for surgical training. Further, they provide novel possibilities for studying the relationship between trabecular bone microstructure and biomechanical properties. (C) 2017 Elsevier B.V. All rights reserved.