STREPTOCOCCI AND AEROCOCCI ASSOCIATED WITH SYSTEMIC INFECTION IN MAN
STREPTOCOCCI AND AEROCOCCI ASSOCIATED WITH SYSTEMIC INFECTION IN MAN
复制标题
DOI：
10.1099/00222615-9-3-275
复制
发表时间：
1976-01-01
影响因子：
3
通讯作者：
BALL, LC
中科院分区：
文献类型：
--
作者：
PARKER, MT;BALL, LC
对820株从人体血液或内脏分离的链球菌和气球菌进行培养和生化鉴定。其中719例（712例链球菌和7例气球菌）来自明显患有全身感染的患者：心内膜炎（317例）;内脏化脓性病变（化脓性疾病）（152例）;和菌血症（250例）。心内膜炎链球菌包括所有可识别分类群的成员，但其中只有一些是常见的：血链球菌，16.4%;葡聚糖阳性，通常是甘露醇发酵的链球菌菌株。牛沙门氏菌（S. bovis）15.1%;变形链球菌14.2%;轻度，13.2%。α-链球菌溶血类群（S. sanguis，S.缓和剂和相关菌株）仅占总数的44.8%。当比较心内膜炎和非心内膜炎分离株中链球菌分类群的百分比频率时，葡聚糖形成分类群（S。mutans、S. bovis I，S. sanguis和类似S.轻度者）都有较高的心内膜炎：非心内膜炎比率，类似于S.缓和剂）都比任何不产生葡聚糖的分类群具有更高的心内膜炎：非心内膜炎比率。心内膜炎的发生率随年龄的增长而增加，在65岁以前，男性多于女性。在年轻患者（< 35岁）中α-溶血性链球菌占优势;随着年龄的增加，其它链球菌的比例逐渐增加，但α-链球菌分离的绝对数量增加。溶血性链球菌没有下降。感染S。变形链球菌以35-54岁年龄组最多见，S.牛的年龄55年了先前心脏病史更经常在由于α-SMA引起的心内膜炎中获得。溶血性链球菌多于其他链球菌性心内膜炎。内脏化脓性病变中最常见的链球菌是链球菌。milleri（29.3%）。合并脑脓肿、脑膜炎、胸腔积脓及各种腹腔积液。心内膜炎唯一常见的诱发因素是既往心脏损伤。在其他系统性链球菌病中，可观察到其他全身或局部诱因，主要见于化脓性可分组链球菌、肠球菌和链球菌感染。米勒里
Isolates (820) of streptococci and aerococci from human blood or internal organs were classified by cultural and biochemical tests. Of these, 719 (712 streptococci and 7 aerococci) were from patients apparently suffering from a systemic infection: endocarditis (317); purulent lesion in an internal organ (purulent disease, (152); and bacteriemia (250). The endocarditis streptococci included members of all recognizable taxa, but only some of these were common: Streptococcus sanguis, 16.4%; dextran-positive and usually mannitol-fermenting strains of S. bovis, 15.1%; S. mutans, 14.2%; S. mitior, 13.2%. Streptococci of the .alpha.-hemolytic taxa (S. sanguis, S. mitior and related strains) formed only 44.8% of the total. When the percentage frequency of streptococcal taxa among the endocarditis and non-endocarditis isolates was compared, the dextran-forming taxa (S. mutans, S. bovis I, S. sanguis, and dextran-positive streptococci otherwise resembling S. mitior) all had higher endocarditis: non-endocarditis ratios resembling S. mitior) all had higher endocarditis: non-endocarditis ratios than did any of the non-dextran-producing taxa. Endocarditis increased in frequency with age, and showed an excess of males over females up to the age of 65 yr. In young patients (< 35 yr) .alpha.-hemolytic streptococci predominated; with increasing age, the proportion of other streptococci increase progressively but the absolute numbers of isolations of .alpha.-hemolytic streptococci did not fall. Infections with S. mutans were prominent in the age group 35-54 yr and with S. bovis at ages .gtoreq. 55 years. A history of previous heart disease was more often obtained in endocarditis due to .alpha.-hemolytic streptococci than in other streptococcal endocarditis. The Streptococcus most often isolated from purulent lesions in internal organs was S. milleri (29.3%). It was associated with brain abscess, meningitis, pleural empyema and a variety of intra-abdominal abscesses. The only common predisposing factor in endocarditis was previous heart damage. In other systemic streptococcal diseases, other general or local predisposing causes could be observed, mainly in infections with the pyogenic groupable streptococci, the enterococci and S. milleri.