Evolution of sex: Using experimental genomics to select among competing theories
Evolution of sex: Using experimental genomics to select among competing theories
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DOI：
10.1002/bies.201600074
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发表时间：
2016-06
期刊：
影响因子：
4
通讯作者：
Nathaniel P. Sharp;S. Otto
中科院分区：
文献类型：
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作者：
Nathaniel P. Sharp;S. Otto
很少有话题能像性的进化那样引起生物学家的兴趣。理解为什么性爱在付出代价的情况下依然存在，不仅需要严格的理论研究，还需要关于相关基本问题的经验数据，包括适应的遗传变异的性质、遗传相互作用的模式和适应的动态。在实验背景下检查基因组的可能性越来越大，这现在为这些问题提供了新的曙光。使用这种方法，麦克唐纳等人。最近证明，不发生性行为的夫妇会发生有益和有害的突变，这使得有性行为时的选择比没有性行为时更有效。在这里，我们在性别进化的主要理论模型的背景下，讨论这项研究提供的见解，以及其他最近的经验性工作。
Few topics have intrigued biologists as much as the evolution of sex. Understanding why sex persists despite its costs requires not just rigorous theoretical study, but also empirical data on related fundamental issues, including the nature of genetic variance for fitness, patterns of genetic interactions, and the dynamics of adaptation. The increasing feasibility of examining genomes in an experimental context is now shedding new light on these problems. Using this approach, McDonald et al. recently demonstrated that sex uncouples beneficial and deleterious mutations, allowing selection to proceed more effectively with sex than without. Here we discuss the insights provided by this study, along with other recent empirical work, in the context of the major theoretical models for the evolution of sex.