PRIMARY LIVER-CANCER - PATTERN OF METASTASIS
PRIMARY LIVER-CANCER - PATTERN OF METASTASIS
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DOI：
10.1002/jso.2930360107
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发表时间：
1987-09-01
影响因子：
2.5
通讯作者：
GEER, DA
中科院分区：
文献类型：
--
作者：
LEE, YTM;GEER, DA
本文对43例原发性肝癌的死亡原因和转移方式进行了分析和讨论，并与文献报道进行了比较。最近6份报告的1673名患者的数据显示，肝癌的三大死因是肝功能衰竭(34%)、出血(30%)和晚期癌症(24%)。对7份报告中的1,497例肝癌患者的转移部位进行了分析，发现前3位转移部位分别为：肺(中位数44%)、门静脉(35%)和门脉淋巴结(S)(27%)。肝硬化性肝癌与非肝硬化性肝癌的转移方式有所不同，前者较易累及门静脉，而后者较易累及区域淋巴结(S)。与肝癌相比，胆管细胞癌转移到肺或门静脉的可能性较小，但更有可能累及淋巴结(S)、腹膜、骨和/或骨髓。
The causes of death and patterns of metastasis of 43 patients with primary liver cancer were studied and discussed in comparison with reports in the literature. Data from 6 recent reports of 1,673 patients showed that the 3 leading causes of death from hepatoma were liver failure (34%), bleeding (30%), and advanced cancer (24%). Distribution of sites of metastasis in 1,497 patients with hepatoma from 7 reports showed that the 3 leading sites were: lung (median 44%), portal vein (35%), and portal lymph node(s) (27%). The pattern of metastasis of hepatoma arising from cirrhotic liver is somewhat different from that of the noncirrhotic liver; the former are more likely to involve the portal vein, whereas the latter involves more regional lymph node(s). Compared to hepatoma, cholangio‐carcinoma is less likely to metastasize to the lung or portal vein, but more likely to involve lymph node(s), peritoneum, and bone and/or marrow.