Psychological consequences of COVID-19 pandemic in Italian MS patients: signs of resilience?
Psychological consequences of COVID-19 pandemic in Italian MS patients: signs of resilience?
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DOI：
10.1007/s00415-020-10099-9
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发表时间：
2020-07-28
影响因子：
6
通讯作者：
Gallo, Antonio
中科院分区：
文献类型：
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作者：
Capuano, Rocco;Altieri, Manuela;Gallo, Antonio
背景焦虑、抑郁和生活质量下降在多发性硬化症患者中很常见。对因COVID-19而生病的恐惧、政府的封锁和强加的社交距离可能对心理困扰和生活质量产生了影响。目的本研究旨在调查意大利SARS-CoV-2爆发期间和封锁期间，SARS患者的焦虑、抑郁和生活质量的变化。方法在意大利SARS-CoV-2爆发前（T0）对67例既往（少于6个月）接受过神经心理学评估的患者在爆发和封锁时（T1）进行重新评估。他们接受了临床和神经学评价，并在T0和T1完成了状态-特质焦虑量表（STAI-Y1）、贝克抑郁量表第二版（BDI-II）和多发性硬化症生活质量-54（MsQoL-54）。采用Benjamini-Hochberg程序控制错误发现率。结果T0和T1时BDI-II和STAI-Y1评分无变化。T1时，MsQoL-54评分在性生活满意度和社会功能子量表上较高，而在情感问题子量表上较低。结论这是第一项评估因COVID-19大流行而封锁前和封锁期间情绪和生活质量水平的研究。焦虑和抑郁水平没有恶化，但生活质量有所改善，其中最可靠的是性满意度和社会功能。
Background Anxiety, depression and reduction of quality of life (QoL) are common in people with multiple sclerosis (pwMS). Fear of getting sick from COVID-19, government's lockdown and the imposed social distancing might have had an impact on psychological distress and QoL. Objectives The aim of our study was to investigate anxiety, depression and QoL changes in pwMS during SARS-CoV-2 outbreak and lockdown in Italy. Methods 67 pwMS with a previous (less than 6 months) neuropsychological evaluation before SARS-CoV-2 outbreak (T0) were re-evaluated at the time of the outbreak and lockdown in Italy (T1). They underwent a clinical and neurological evaluation and completed the State-Trait Anxiety Inventory (STAI-Y1), the Beck Depression Inventory second edition (BDI-II), and Multiple Sclerosis Quality of Life-54 (MsQoL-54) at T0 and T1. Benjamini-Hochberg procedure was applied to control the false discovery rate. Results BDI-II and STAI-Y1 scores did not change between T0 and T1. At T1, MsQoL-54 scores were higher on the satisfaction with sexual life and the social function subscales, and lower on the limitation due to emotional problems subscale. Conclusions This is the first study that evaluated mood and QoL levels before and during the lockdown due to COVID-19 pandemic in pwMS. No worsening of anxiety and depression levels was found. Contrariwise some improvements were noted on QoL, the most reliable regarding the sexual satisfaction and the social function.