Bioanalytical Applications of Au Nanoparticles
Bioanalytical Applications of Au Nanoparticles
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DOI：
10.2174/187221010790712075
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发表时间：
2010-01-01
影响因子：
2
通讯作者：
Raj, C. Retna
中科院分区：
文献类型：
--
作者：
Jena, Bikash K.;Ghosh, Sourov;Raj, C. Retna
纳米级Au粒子由于其独特的性质而受到人们的广泛关注。虽然胶体Au自古以来就被认为是玻璃的装饰和治疗能力，但其技术重要性直到最近二十年才被认识。Au纳米粒子具有独特的光学和电学性质，使其成为开发纳米器件的理想材料。大量的研究致力于探索这些微小颗粒的技术应用。基于Au纳米颗粒的各种生物传感器件、催化界面和生物分析方法在过去二十年中已经被开发用于不同的应用。Au纳米粒子被认为是21（st）世纪新兴的纳米能量和传感器件的关键构件。在这篇综述中，我们重点介绍了Au纳米粒子的生物分析应用的一些最新专利和相关文献。简要概述了各种尺寸和形状的Au纳米颗粒的合成，并详细介绍了它们在光学和电化学传感器/生物传感器和药物输送分析方法的发展中的潜在用途。
Nanoscale Au particles are received with significant interest in the recent years owing to their unique properties, which originate from the quantum scale dimension. Although colloidal Au has been known since ancient times for the decoration of glasses and for its curative powers, the technological importance has been understood only in the last two decades. The fascinating optical and electronic properties of the Au nanoparticles made them an excellent candidate in the development of nanoscale devices. Significant amount of research has been devoted to explore the technological application of these tiny particles. Various biosensing devices, catalytic interfaces and bioanalytical methodologies based on Au nanoparticles have been developed in the last two decades for different applications. Au nanoparticles are considered to be the key building blocks in the emerging nanoscale energy and sensing devices of 21(st) century. In this review, we highlight some of the recent patents and related literature on the bioanalytical applications of Au nanoparticles. A brief outline on the synthesis of Au nanoparticles of various size and shape and a detailed account of their potential utilization in the development of optical and electrochemical sensors/biosensors and analytical methods for drug delivery are discussed.