Tackling host-circuit give and take.
Tackling host-circuit give and take.
复制标题
解决主机电路的交换问题。
DOI：
10.1038/s41564-017-0058-6
复制
发表时间：
2017
影响因子：
28.3
通讯作者：
Brynildsen,MarkP
中科院分区：
文献类型：
--
作者：
Aedo,SandraJ;Gelderman,Grant;Brynildsen,MarkP
将额外的基因回路并入宿主通常会导致不可预测和不受欢迎的行为。最近的工作开发了一个建模框架，该框架考虑了宿主电路相互作用，并可以在单细胞和群体水平上预测各种表型。
The incorporation of additional gene circuits into hosts can often lead to unpredicted and undesirable behaviours. Recent work has developed a modelling framework that accounts for host–circuit interactions and can predict a variety of phenotypes at both single-cell and population levels.