HETEROGENEITY OF HUMORAL IMMUNE COMPONENTS IN HUMAN CYSTICEROCOSIS
HETEROGENEITY OF HUMORAL IMMUNE COMPONENTS IN HUMAN CYSTICEROCOSIS
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DOI：
10.2307/3281420
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发表时间：
1985-01-01
影响因子：
1.3
通讯作者：
FLISSER, A
中科院分区：
文献类型：
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作者：
CORREA, D;DALMA, D;FLISSER, A
用免疫荧光法检测了12只猪带绦虫囊尾蚴表面IgG、IgM、伊加、IgE和C_3b。本文报道了4种免疫球蛋白的抗囊虫抗体在神经系统疾病患者的脑脊液、眼囊尾蚴病患者的眼内体液和部分患者的血清中的检测结果。记录寄生虫的形态学外观以及患者的临床特征。组分的分布是异质性的不同寄生虫表面。不同虫体表面以IgG最常见，其次为伊加、IgM，C3b具有异质性。以IgG最常见，其次为伊加、IgM、C3b和IgE。这些分子的存在与囊尾蚴损伤的迹象之间没有相关性，或者与作为抗囊尾蚴抗体的免疫球蛋白类之间没有相关性。可能的解释，这些发现以及在囊虫病的异质性的影响进行了讨论。
Twelve Taenia solium cysticerci, obtained from several human organs, were examined by immunofluorescence for IgG, IgM, IgA, IgE and C3b on their surfaces. Anti-cysticercus antibodies of the 4 classes of immunoglobulins were looked for in the cerebrospinal fluid of most neurologic patients, in the intraocular humors of a patient wth eye cysticercosis, and in the serum of some other patients. The morphological appearance of the parasites as well as the clinical features of the patients were recorded. The distribution of components was heterogeneous among the different parasite surfaces. IgG was the most frequent, followed by IgA, IgM, C3b was heterogenous among the different parasite surfaces. IgG was the most frequent, followed by IgA, IgM, C3b and IgE. No correlation was found between the presence of these molecules and signs of damage in the cysticerci, or with the classes of immunoglobulins found as anti-cysticercus antibodies. Possible explanations of these findings as well as the implications of heterogeneity in cysticercosis are discussed.