FEMORAL AND POPLITEAL ARTERIES - REANALYSIS OF RESULTS OF BALLOON ANGIOPLASTY

FEMORAL AND POPLITEAL ARTERIES - REANALYSIS OF RESULTS OF BALLOON ANGIOPLASTY
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DOI:
10.1148/radiology.183.3.1294068
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发表时间:
1992-06-01
期刊:
影响因子:
19.7
通讯作者:
JOHNSTON, KW
JOHNSTON, KW
中科院分区:
医学1区
文献类型:
--
作者:
JOHNSTON, KW

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作者对多伦多大学系列股动脉和腘动脉经皮腔内血管成形术(PTA)的结果进行了替代统计分析(n = 254)。 采用Kaplan-Meier方法重新计算数据后,术后成功率范围为1个月时的88.8% +/- 2.0至6年时的35.7% +/- 4.8。 经考克斯多元回归分析,股腘病变类型和流出量是预测远期疗效的有用变量。 对于径流良好的狭窄,5年时的成功率为53%;径流不良的狭窄,5年时的成功率为31%。 对于具有良好径流的闭塞,5年时的成功率为36%;具有不良径流的闭塞,5年时的成功率为16%。 在最初成功的病例中,PTA时径流良好的患者在1年、3年和5年的持续临床成功率优于径流不良的患者。 由于最近的研究已经证明股腘动脉PTA的技术成功率有所提高,因此似乎有必要对PTA与手术的相对安全性、长期临床疗效和累积成本进行比较研究。
The author presents an alternative statistical analysis of the results of the University of Toronto series of percutaneous transluminal angioplasty (PTA) of the femoral and popliteal arteries (n = 254). After recalculation of the data with the Kaplan-Meier method, the postprocedure success rate ranged from 88.8% +/- 2.0 at 1 month to 35.7% +/- 4.8 at 6 years. With Cox multiple regression analysis, the type of femoropopliteal lesion and the runoff were the variables that were useful to predict late results. For stenoses with good runoff, the success rate was 53% at 5 years; with poor runoff, 31% at 5 years. For occlusions with good runoff, the success rate was 36% at 5 years; with poor runoff, 16% at 5 years. In initially successful cases, ongoing clinical success at 1, 3, and 5 years was better in patients with good runoff at the time of PTA than in those with poor runoff. Now that more recent studies have documented improved technical success in femoropopliteal PTA, a comparative study of the relative safety, long-term clinical efficacy, and cumulative cost of PTA versus surgery seems warranted.