Efficient synthesis of dendrimers via a thiol-yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs

Efficient synthesis of dendrimers via a thiol-yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs
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DOI:
10.1039/b910340f
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发表时间:
2009-01-01
影响因子:
4.9
通讯作者:
Stenzel, Martina H.
Stenzel, Martina H.
中科院分区:
化学2区
文献类型:
--
作者:
Chen, Gaojian;Kumar, Jatin;Stenzel, Martina H.

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硫醇-炔化学和酯化反应的组合成功地应用于通过发散生长策略制备具有一系列末端官能团的树枝状聚合物;最大化反应性链端的数量,同时最小化过程中所需的反应步骤的数量。
A combination of thiol-yne chemistry and esterification reactions were successfully applied for the preparation of dendrimers with an array of terminal functionalities via the divergent growth strategy; maximizing the number of reactive chain ends whilst minimizing the number of reaction steps required in the process.