Trends in the total numbers of HBV and HCV carriers in Japan from 2000 to 2011
Trends in the total numbers of HBV and HCV carriers in Japan from 2000 to 2011
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DOI：
10.1111/jvh.12828
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发表时间：
2018-04-01
影响因子：
2.5
通讯作者：
Satake, M.
中科院分区：
文献类型：
--
作者：
Tanaka, J.;Akita, T.;Satake, M.
我们根据2011年期间的自然病史分类，估计了日本未确诊的HBV和HCV携带者以及肝炎病毒相关疾病患者的总数。2011年，使用政府报告和日本厚生劳动省肝炎流行病学研究小组的报告，根据6组估计了HBV或HCV感染的携带者和患者总数。2011年，肝炎病毒携带者总数估计为2090128-2840128，其中未确诊的HCV和HBV携带者估计为776826（HBV：481470; HCV：295356）。2011年，接受治疗的患者总数（住院患者或门诊患者）估计为811588例（HBV：303366例; HCV：520600例）。据推测，许多携带者逃避咨询的原因是多方面的，如病人的误解，缺乏认识和忘记自己的积极地位。2011年，未寻求治疗的感染患者人数逐渐增加至501714-1251714人（HBV：333791-483791; HCV：167923-767923）。与2000年相比，2011年未确诊的携带者人数大幅减少，这可能是因为日本政府自2002年以来启动了组织良好、有效的全国肝炎病毒筛查系统。此外，知道自己呈阳性的未接受治疗的人数增加，这表明应作出更多努力，改善从筛查中心到核心医院的转诊制度。
We estimated the total number of undiagnosed HBV and HCV carriers and patients with hepatitis virus-related disease in Japan according to 6 different groups classified by their natural histories during 2011. In 2011, the total number of carriers and patients infected with HBV or HCV was estimated according to 6 groups using government reports and reports from the hepatitis epidemiology research group of The Ministry of Health, Labor and Welfare in Japan. In 2011, the total number of hepatitis virus carriers was estimated to be 2090128-2840128 in which the estimated number of undiagnosed HCV and HBV carriers was 776826 (HBV: 481470; HCV: 295356). The total number of treated patients, as either inpatients or outpatients, was estimated to be 811588 (HBV: 303366; HCV: 520600) in 2011. It is presumed that many carriers shirk consultation for many reasons, such as patients' misunderstanding, lack of awareness and forgetfulness of their positive status. The numbers of infected patients who did not seek treatment increased gradually to 501714-1251714 (HBV: 333791-483791; HCV: 167923-767923) in 2011. Compared to 2000, the number of undiagnosed carriers was significantly reduced in 2011 probably because of the well-organized, effective national hepatitis virus screening system that has been launched by the Japanese government since 2002. Moreover, the increase in the number of untreated persons who are aware of their positive status shows that more effort should be invested in improving the referral system from screening centres to core hospitals.