The postnatal development of lymphoreticular aggregates and lymph nodes in infants' lungs
The postnatal development of lymphoreticular aggregates and lymph nodes in infants' lungs
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婴儿肺部淋巴网状聚集体和淋巴结的出生后发育
DOI：
10.1136/jcp.26.7.539
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发表时间：
1973
影响因子：
3.4
通讯作者：
F. Dinsdale
中科院分区：
文献类型：
--
作者：
J. Emery;F. Dinsdale
对 316 名儿童肺右中叶的标准化切片进行了定量研究。没有表现出病理状态的肺部表明淋巴结在出生时就存在，并且在出生后的第一年，这些淋巴结的数量即使不是数量上的增加，也会明显增加。出生时正常婴儿肺的肺泡中不存在淋巴网状聚集物。这些症状在出生后一周左右首次出现，并在婴儿期和幼儿期逐渐增加，到 5 岁时几乎普遍出现。婴儿肺部外周淋巴网状聚集体的发育似乎完全受到环境和抗原的刺激。
A quantitative study has been made of standardized sections taken from the right middle lobe of 316 children's lungs. Lungs showing no pathological state showed that lymph nodes are present at birth and these increase in prominence if not in numbers throughout the first year after birth. Lymphoreticular aggregates are not present among the alveoli of the normal infant lung at birth. These first appear around a week after birth and progressively increase in number throughout infancy and early childhood, being almost universally present by the age of 5 years. The development of peripheral lymphoreticular aggregates in the lungs of infants appears to be entirely environmentally and antigenically stimulated.