Hepatitis C infection in hemodialysis patients in Iran: A systematic review
Hepatitis C infection in hemodialysis patients in Iran: A systematic review
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DOI：
10.1111/j.1542-4758.2010.00437.x
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发表时间：
2010-07-01
影响因子：
1.3
通讯作者：
Ahmadzad-Asl, Masoud
中科院分区：
文献类型：
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作者：
Alavian, Seyed-Moayed;Kabir, Ali;Ahmadzad-Asl, Masoud
血液透析患者是公认的丙型肝炎病毒感染的高危人群之一。在不同的伊朗人群中，丙型肝炎病毒感染的流行率差异很大，在5.5%到24%之间。降低这些患者中丙型肝炎病毒感染率的预防计划需要准确的信息。在目前的研究中，我们估计了伊朗HD患者中丙型肝炎病毒感染的流行率。在这项系统性综述中，我们收集了2001年4月至2008年3月期间所有已发表和未发表的关于伊朗HD患者中丙型肝炎病毒感染流行率的文献。我们选择了描述性/分析性横断面研究/调查，这些研究/调查具有充分宣布的目标，对所有研究对象具有相同和有效测量工具的适当抽样方法，以及关于抽样设计和人口统计调整的适当分析方法。我们使用Meta分析方法计算了全国的患病率估计。来自12个省的18项研究(占伊朗总人口的49.02%)报告了伊朗HD患者中丙型肝炎病毒感染的流行率。重组免疫印迹法检测伊朗HD患者的丙型肝炎病毒感染率为7.61%(95%可信区间：6.06-9.16%)。伊朗是血液透析患者中丙型肝炎感染率较低的国家之一。
Hemodialysis (HD) patients are recognized as one of the high-risk groups for hepatitis C virus (HCV) infection. The prevalence of HCV infection varies widely between 5.5% and 24% among different Iranian populations. Preventive programs for reducing HCV infection prevalence in these patients require accurate information. In the present study, we estimated HCV infection prevalence in Iranian HD patients. In this systematic review, we collected all published and unpublished documents related to HCV infection prevalence in Iranian HD patients from April 2001 to March 2008. We selected descriptive/analytic cross-sectional studies/surveys that have sufficiently declared objectives, a proper sampling method with identical and valid measurement instruments for all study subjects, and proper analysis methods regarding sampling design and demographic adjustments. We used a meta-analysis method to calculate nationwide prevalence estimation. Eighteen studies from 12 provinces (consisting 49.02% of the Iranian total population) reported the prevalence of HCV infection in Iranian HD patients. The HCV infection prevalence in Iranian HD patients is 7.61% (95% confidence interval: 6.06-9.16%) with the recombinant immunoblot assay method. Iran is among countries with low HCV infection prevalence in HD patients.