Metabolomics in the opening decade of the 21st century: Building the roads to individualized health
Metabolomics in the opening decade of the 21st century: Building the roads to individualized health
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DOI：
10.1093/jn/134.10.2729
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发表时间：
2004-10-01
影响因子：
4.2
通讯作者：
Zeisel, SH
中科院分区：
文献类型：
--
作者：
German, JB;Bauman, DE;Zeisel, SH
测量生物体液或组织小样本中的数百或数千种代谢物正在迅速成为可能。这使得评估营养表型的代谢成分成为可能，并允许个性化的饮食建议。 ASNS 必须采取行动，确保开发适当的技术，并使用正确的输入和组织构建代谢数据库。必须建立饮食和代谢组学特征之间以及这些特征与健康和疾病之间的关系。 ASNS 还应考虑这些进步的社会影响并规划其适当利用。
It is rapidly becoming possible to measure hundreds or thousands of metabolites in small samples of biological fluids or tissues. This makes it possible to assess the metabolic component of nutritional phenotypes and will allow individualized dietary recommendations. ASNS has to take action to ensure that appropriate technologies are developed and that metabolic databases are constructed with the right inputs and organization. The relations between diet and metabolomic profiles and between those profiles and health and disease must be established. ASNS also should consider the social implications of these advances and plan for their appropriate utilization.