Baseline Characteristics of Nearwork-Induced Transient Myopia
Baseline Characteristics of Nearwork-Induced Transient Myopia
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DOI：
10.1097/opx.0b013e3182775e05
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发表时间：
2012-12-01
影响因子：
1.4
通讯作者：
Ciuffreda, Kenneth J.
中科院分区：
文献类型：
--
作者：
Lin, Zhong;Vasudevan, Balamurali;Ciuffreda, Kenneth J.
目的。本研究的目的是描述北京近视进展研究的基线屈光性和近距性短暂性近视（NITM）特征，该研究是一项为期3年的队列研究，其总体具体目的有三个：调查北京市中心城区7 - 17岁学童的NITM自然史；探讨NITM与永久性近视的可能关系；并确定与NITM的可能关联（如亲代史）。共有386名学生（男187人，女199人）被录取。小学生平均年龄8.4 +/- 1.1岁，中学生平均年龄14.2 +/- 1.6岁。基线屈光方面在临床上确定。在双眼观看并执行持续近距离任务（5分钟；5屈光度[D]）后，立即客观评估初始NITM及其衰减，包括认知需求和全距离屈光矫正。综合学校水平，近视、准远视和远视学生的初始NITM（平均+/- SD） /衰减时间（中位数、第一四分位数和第三四分位数）分别为0.18 +/- 0.16 D / 50（20、90）秒、0.09 +/- 0.13 D / 30（10、40）秒和0.10 +/- 0.19 D / 20（10、40）秒。与其他两种屈光组相比，近视组的初始NITM和衰减时间明显更大/更长。本研究结果表明，在大样本的学龄近视儿童中，初始NITM量级明显大于同龄远视或远视儿童，衰减持续时间明显更长。未来3年的随访将有助于了解NITM在永久性近视发展中的可能作用。（光学视觉科学；2012;39:1725-1733）
Purpose. The purpose of the present study was to describe the baseline refractive and nearwork-induced transient myopia (NITM) characteristics of the Beijing Myopia Progression Study, a 3-year cohort study, that has three overall specific aims: to investigate the natural history of NITM in schoolchildren living in the inner city of Beijing aged between 7 and 17 years; to investigate the possible relation between NITM and permanent myopia; and to determine the possible associations with NITM (eg, parental history).Methods. Three hundred eighty-six students (187 males and 199 females) were enrolled. The mean ages were 8.4 +/- 1.1 years and 14.2 +/- 1.6 years for the primary school and secondary school students, respectively. Baseline refractive aspects were determined clinically. Initial NITM and its decay were assessed objectively immediately after binocularly viewing and performing a sustained near task (5 minutes; 5 diopters [D]), incorporating a cognitive demand with full distance refractive correction in place.Results. Initial NITM (mean +/- SD) / decay time (median, first quartile, and third quartile) was 0.18 +/- 0.16 D / 50 (20, 90) seconds, 0.09 +/- 0.13 D / 30 (10, 40) seconds, and 0.10 +/- 0.19 D / 20 (10, 40) seconds among the myopic, emmetropic, and hyperopic students, respectively, for the combined school levels. Initial NITM and decay time were significantly larger/longer in the myopic versus the other two refractive groups.Conclusions. The present findings demonstrate that in a large sample of school-aged children with myopia, the initial NITM magnitude was significantly larger and the decay duration was significantly longer than that observed in age-matched children with either emmetropia or hyperopia. Follow-up for the next 3 years will provide insight into the possible role of NITM in the development of permanent myopia. (Optom Vis Sci 2012; 89: 1725-1733)