Feasibility and behavioral effects of an at-home multi-night sleep restriction protocol for adolescents
Feasibility and behavioral effects of an at-home multi-night sleep restriction protocol for adolescents
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DOI：
10.1111/j.1469-7610.2008.01885.x
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发表时间：
2008-09-01
影响因子：
7.6
通讯作者：
Amin, Raouf
中科院分区：
文献类型：
--
作者：
Beebe, Dean W.;Fallone, Gahan;Amin, Raouf
背景：睡眠不足在青少年中很常见，并与不良行为和教育结果相关。然而，由于缺乏实验性睡眠研究，很难得出强有力的因果结论。在某种程度上，这似乎与与这一人群合作时的方法挑战有关。这项研究在青少年样本中测试了多晚在家实验性睡眠限制方案的可行性和行为影响。方法：采用平衡交叉实验设计，对 20 名 13.9-16.9 岁的健康青少年进行了为期三周的睡眠操纵方案。该方案包括基线周，然后按随机顺序进行短睡眠周（周一至周五晚上床上时间限制为 6.5 小时）和延长睡眠周（周一至周五晚上在床上睡觉 10 小时熄灯时间）。通过自我报告和客观体动记录仪监测睡眠。每周末的周六，参与者和家长都会对这些内容进行审查，同时家长和参与者还完成了行为评级调查问卷。结果：一名参与者退出了研究，但其余 19 名参与者在短睡眠条件下的睡眠明显少于长睡眠条件下的睡眠（平均每晚睡眠间隔约为 2.5 小时）。数据还反映了睡眠剥夺的间接影响，这与稳态睡眠驱动力的增加是一致的。与延长睡眠周相比，短睡眠周的父母报告说，参与者在困倦、注意力、对立/易怒、行为调节和元认知方面表现出明显更大的问题。参与者的自我报告结果相似，但不太稳健。结论：针对青少年使用的多晚在家睡眠控制方案确实可行。这项研究还提供了第一个实验证据，表明青春期长期睡眠限制与多种行为缺陷存在因果关系。
Background: Sleep deprivation is common among adolescents and has been associated with adverse behavioral and educational outcomes. However, it is difficult to draw strong causal conclusions because of a dearth of experimental sleep research. In part, this appears related to methodological challenges when working with this population. This study tested the feasibility and behavioral effects of a multi-night, at-home experimental sleep restriction protocol in a sample of adolescents. Methods:Twenty healthy adolescents aged 13.9-16.9 years were enrolled in a three-week sleep manipulation protocol using a counterbalanced cross-over experimental design. The protocol included a baseline week, followed in random order by a short sleep week (Monday-Friday nights limited to 6.5 hours time in bed) and an extended sleep week (10 hours lights-out time in bed Monday-Friday nights). Sleep was monitored via self-report and objective actigraphy. These were reviewed with participants and parents on the Saturdays at the end of each week, when parents and participants also completed behavior rating questionnaires. Results: One participant dropped out of the study, but each of the remaining 19 displayed markedly less sleep in the short sleep condition than the extended sleep condition (average nightly gap similar to 2.5 hours). Data also reflected indirect effects of sleep deprivation that are consistent with an increase in homeostatic sleep drive. Compared to the extended sleep week, parents during the short sleep week reported that the participants displayed significantly greater problems with sleepiness, attention, oppositionality/irritability, behavior regulation, and metacognition. Participant self-report results were similar, though less robust. Conclusions: A multi-night, at-home sleep manipulation protocol for use with adolescents is indeed feasible. This study also provided the first experimental evidence that chronic sleep restriction during adolescence is causally related to a wide range of behavioral deficits.