Effects of indoor low humidity on eye discomfort and associated physiological responses in soft contact lens and non-lens wearers
Effects of indoor low humidity on eye discomfort and associated physiological responses in soft contact lens and non-lens wearers
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DOI：
10.1177/1420326x221126352
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发表时间：
2022-09
影响因子：
3.6
通讯作者：
Kanoko Ito;S. Takada
中科院分区：
文献类型：
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作者：
Kanoko Ito;S. Takada
干燥引起的眼睛不适是室内空间报告的主要抱怨之一。本研究的目的是定量评估低湿度对软性隐形眼镜(SCL)和非软性隐形眼镜佩戴者眼睛不适的影响。除了主观感觉外，与眼睛不适有关的生理参数，包括泪膜参数和眨眼模式，在23°C的相对湿度为10%和45%时进行了比较评估。对于SCL组和非CL佩戴者组，低湿度对一些测量的生理参数有显著影响。SCL组在10%相对湿度(RH)下眨眼后的眼表温度低于45%RH时的眼表温度，而眼表温差大于45%RH时的温差，表明泪液蒸发更快。此外，在RH为10%时，它们的泪膜比在RH为45%时更薄，破裂时间更短。非CL组在10%RH时的眨眼频率和闭眼时间显著高于45%RH组，这可能是对低湿度引起的泪膜干扰的一种代偿反应。这些结果表明，就泪膜质量而言，室内空间湿度控制的重要性，这会导致眼睛不适。
Eye discomfort due to dryness is one of the major complaints reported in indoor spaces. The purpose of this study was to quantitatively evaluate the effect of low humidity on eye discomfort in soft contact lens (SCL) and non-CL wearers. In addition to subjective sensations, physiological parameters related to eye discomfort including tear-film parameters and blink patterns were comparatively evaluated between relative humidities of 10% and 45% at 23°C. For both the SCL and non-CL wearer groups, low humidity had a significant effect on some of the measured physiological parameters. The SCL group showed lower ocular surface temperature and larger temperature differential after blinking at 10% relative humidity (RH) than that at 45% RH, indicating faster tear evaporation. Furthermore, their tear films tended to be thinner and have a shorter break-up time at 10% RH than at 45% RH. The non-CL group showed a significantly higher blink frequency and longer eye-closure time at 10% RH than at 45% RH, presumably as a compensatory response to the disturbance of the tear film due to low humidity. These results suggest the importance of humidity control in indoor spaces in terms of tear-film quality, which contributes to eye discomfort.