Delivery of plasmid DNA to mammalian cells using polymer-gold nanorod assemblies.
Delivery of plasmid DNA to mammalian cells using polymer-gold nanorod assemblies.
复制标题
使用聚合物-金纳米棒组件将质粒 DNA 递送至哺乳动物细胞。
DOI:
10.1007/978-1-62703-336-7_9
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发表时间:
2013
期刊:
影响因子:
--
通讯作者:
Rege,Kaushal
中科院分区:
文献类型:
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作者:
Ramos,James;Huang,Huang-Chiao;Rege,Kaushal
Functionalized and surface-modified gold nanorods (GNRs) have emerged as promising vehicles for the delivery of several therapeutic agents. Ease of functionalization, increased stability, biocompatibility, and size-dependent plasmonic properties make gold nanorods attractive in sensing, imaging, and delivery to different cellular types. Here, we demonstrate the use of polyelectrolyte-coated GNRs (PE-GNRs) for delivering plasmid DNA to mammalian cells for transgene expression.