Higher risk of unsafe sex and impaired quality of life among patients not receiving antiretroviral therapy in Cameroon: results from the EVAL survey (ANRS 12-116)-猫眼课题宝

DOI：

10.1097/01.aids.0000366079.83568.a2

发表时间：

2010-01-01

期刊：

AIDS

影响因子：

3.8

通讯作者：

中科院分区：

医学2区

文献类型：

作者：

Marcellin, Fabienne;Bonono, Cecile-Renee;Koulla-Shiro, Sinata

目的：喀麦隆启动了一项艾滋病毒护理权力下放国家方案，为CD 4细胞计数低于200个细胞/μ l或艾滋病阶段的患者提供抗逆转录病毒治疗。目前的临床研究表明，这些标准可能过于严格。本研究旨在评估不接受ART对患者心理社会结果的影响。设计：全国横断面调查EVAL（ANRS 12-116）收集了3151名接受艾滋病毒服务的患者的心理社会和临床数据（2006年9月至2007年3月）。倾向评分匹配用于控制接受ART的患者与未接受ART的患者之间的人口统计学/临床免疫学差异。广义线性模型用于评估不同CD 4细胞水平的“未接受”抗逆转录病毒治疗对健康相关生活质量（HRQoL）的影响、与血清不一致或艾滋病毒状态未知的性伴侣不一致使用避孕套、自我报告的症状以及向亲属或朋友披露艾滋病毒状态。调查中78%的患者正在接受抗逆转录病毒治疗。未接受治疗的患者细分如下：8%（CD 4

Objective: Cameroon has initiated a national programme of HIV care decentralization providing access to antiretroviral therapy (ART) for patients with CD4 cell counts less than 200 cells/mu l or AIDS stage. Current clinical research suggests these criteria may be too stringent. This study aimed at evaluating the effect of not receiving ART on patients' psychosocial outcomes.Design: The national cross-sectional survey EVAL (ANRS 12-116) collected psychosocial and clinical data for 3151 patients attending HIV services (September 2006 to March 2007).Methods: Propensity score matching was used to control for demographic/clinical-immunological differences between patients receiving ART and those who did not. Generalized linear models were used to assess the impact, for different CD4 cell levels, of "not receiving" ART on health-related quality of life (HRQoL) inconsistent condom use with a sexual partner either serodiscordant or of unknown HIV status, self-reported symptoms and disclosure of HIV status to relatives or friends.Results: Seventy-eight per cent of patients included in the survey were receiving ART. Non-treated patient breakdown was as follows: 8% (CD4

Higher risk of unsafe sex and impaired quality of life among patients not receiving antiretroviral therapy in Cameroon: results from the EVAL survey (ANRS 12-116)

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