Measurements of RF heating during 3.0-T MRI of a pig implanted with deep brain stimulator.
Measurements of RF heating during 3.0-T MRI of a pig implanted with deep brain stimulator.
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DOI：
10.1016/j.mri.2012.11.005
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发表时间：
2013-06
影响因子：
2.5
通讯作者：
Bernstein, Matt A.
中科院分区：
文献类型：
--
作者：
Gorny, Krzysztof R.;Presti, Michael F.;Goerss, Stephan J.;Hwang, Sun C.;Jang, Dong-Pyo;Kim, Inyong;Min, Hoon-Ki;Shu, Yunhong;Favazza, Christopher P.;Lee, Kendall H.;Bernstein, Matt A.
介绍植入脑深部电刺激（DBS）系统的猪在MRI期间的初步体内温度测量结果。DBS系统（Medtronic Inc.，Minneapolis，MN）植入麻醉猪的脑中。使用T/R头部线圈进行3.0T MRI，使用低SAR GRE EPI和IR准备GRE序列（SAR：分别为0.42 W/kg和0.39 W/kg）和高SAR 4回波RF自旋回波（SAR：2.9 W/kg）。使用荧光测温法直接测量DBS电极和植入式脉冲发生器（IPG）的射频相关产热。作为参考，在1.5T和两种场强下，在体模中对同一只猪重复测量。在3.0 T时，DBS电极的最大温升分别为0.46 °C和2.3 °C（对于低SAR和高SAR序列）。在任何测量过程中，均未观察到植入的IPG发热。体内加热的测量值与体模中获得的测量值不同。使用GRE EPI和IR准备GRE序列的3.0T MRI导致DBS电极的局部温度升高不超过0.46°C。虽然不应外推到人体检查，还需要进一步研究，但这些初步数据对于DBS患者未来使用3.0T MRI是令人鼓舞的。
To present preliminary, in vivo temperature measurements during MRI of a pig implanted with a deep brain stimulation (DBS) system. DBS system (Medtronic Inc., Minneapolis, MN) was implanted in the brain of an anesthetized pig. 3.0T MRI was performed with a T/R head coil using the low-SAR GRE EPI and IR-prepped GRE sequences (SAR: 0.42 W/kg and 0.39 W/kg, respectively), and the high-SAR 4-echo RF spin echo (SAR: 2.9 W/kg). Fluoroptic thermometry was used to directly measure RF-related heating at the DBS electrodes, and at the implantable pulse generator (IPG). For reference the measurements were repeated in the same pig at 1.5T and, at both field strengths, in a phantom. At 3.0T, the maximal temperature elevations at DBS electrodes were 0.46 °C and 2.3 °C, for the low- and high-SAR sequences, respectively. No heating was observed on the implanted IPG during any of the measurements. Measurements of in-vivo heating differed from those obtained in the phantom. The 3.0T MRI using GRE EPI and IR-prepped GRE sequences resulted in local temperature elevations at DBS electrodes of no more than 0.46°C. Although no extrapolation should be made to human exams and much further study will be needed, these preliminary data are encouraging for the future use 3.0T MRI in patients with DBS.
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影响因子：
--
作者：
Bronstein JM;Tagliati M;Alterman RL;Lozano AM;Volkmann J;Stefani A;Horak FB;Okun MS;Foote KD;Krack P;Pahwa R;Henderson JM;Hariz MI;Bakay RA;Rezai A;Marks WJ Jr;Moro E;Vitek JL;Weaver FM;Gross RE;DeLong MR
通讯作者：
DeLong MR
影响因子：
5.7
作者：
Erickson, KM;Lanier, WL
通讯作者：
Lanier, WL
影响因子：
3.5
作者：
Mattei, E.;Triventi, M.;Bartolini, P.
通讯作者：
Bartolini, P.
影响因子：
16.2
作者：
Mayberg, HS;Lozano, AM;Kennedy, SH
通讯作者：
Kennedy, SH
影响因子：
8.8
作者：
KURZ, A;SESSLER, DI;DECHERT, M
通讯作者：
DECHERT, M