Dietary evaluation and attenuation of relative risk: Multiple comparisons between blood and urinary biomarkers, food frequency, and 24-hour recall questionnaires: the DEARR study
Dietary evaluation and attenuation of relative risk: Multiple comparisons between blood and urinary biomarkers, food frequency, and 24-hour recall questionnaires: the DEARR study
复制标题
DOI：
10.1093/jn/135.3.573
复制
发表时间：
2005-03-01
影响因子：
4.2
通讯作者：
Fraser, D
中科院分区：
文献类型：
--
作者：
Shai, I;Rosner, BA;Fraser, D
饮食疾病相对风险(RR)的估计受到膳食测量误差引入的不准确的影响。使用“三联法”，通过FFQ、参考方法和生物标记物之间的3对相关关系，可以估计饮食评估方法的有效性系数(VC)和“真实”长期摄入量，作者对新开发的FFQ的表现进行了评估。在13个月的时间里(2000年9月至2001年9月)，161名参与者完成了3次FFQ和6次24小时召回(24小时)，并提供了2份血液样本和3次24小时尿液采集。对于蛋白质、β-胡萝卜素和叶酸，“真实摄入量”的VCs值(分别为0.77、0.65和0.72)相对高于24小时的VCs值(分别为0.68、0.60和0.39)。在生物标志物中，血清β-胡萝卜素和叶酸的VC值(0.65和0.65)高于尿氮和α-生育酚的VC值(0.44和0.34)。DEARR的研究表明，新开发的FFQ是一种评估膳食摄入量的有效和可重复的工具。所获得的VC可用于未来调整该人群的饮食-疾病RR估计。
Estimates of diet-disease relative risks (RRs) suffer from inaccuracies introduced by dietary measurement errors. Using the "method of triads," by which the validity coefficient (VC) of the dietary assessment method and "true" long-term intake could be estimated from 3 pairwise correlations between the FFQ, the reference method, and the biomarker, the authors evaluated the performance of a newly developed FFQ. Over a period of 13 mo (September 2000 to September 2001), 161 participants completed 3 FFQs and six 24-h recalls (24HRs), and supplied 2 blood samples and three 24-h urine collections. For protein, beta-carotene, and folic acid, the VCs of the FFQ with the "true intake" (0.77, 0.65, and 0.72, respectively) were relatively higher than the VCs of 24HRs (0.68, 0.60 and 0.39, respectively). Among the biomarkers, the VCs of serum p-carotene and folic acid with the "true intake" (0.65 and 0.65) were higher than the VCs of urinary nitrogen and a-tocopherol (0.44 and 0.34, respectively). The DEARR study showed that the newly developed FFQ is a valid and reproducible instrument for assessing dietary intake. The VCs obtained can be used for future adjustment of diet-disease RR estimates in this population.