Characteristic Features of the Interictal EEG Background in 2 Patients With Malignant Migrating Partial Epilepsy in Infancy.
Characteristic Features of the Interictal EEG Background in 2 Patients With Malignant Migrating Partial Epilepsy in Infancy.
复制标题
2名恶性迁移的患者在婴儿期迁移的患者中，发作性脑电图背景的特征。
DOI：
10.1097/wnp.0000000000000178
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发表时间：
2015-08
期刊：
影响因子：
--
通讯作者：
Erba G
中科院分区：
文献类型：
--
作者：
Selioutski O;Seltzer LE;Burchfiel J;Paciorkowski AR;Erba G
目的：描述两例MMPEI患者从新生儿到婴儿期发作间期脑电背景的时间序列特征。两名符合MMPEI诊断标准的患者在6个月的时间里采集了脑电图，以监测治疗效果并表征癫痫发作和其他发作事件。两名患者都遵循相似的顺序模式。在发作间期背景变得连续之前，观察到从不成熟的足月新生儿脑电模式到异步抑制猝发模式的独特演变。为患有顽固性癫痫和突发抑制EEG模式的婴儿提供护理的医生应警惕MMPEI的可能性。早期诊断MMPEI将有助于指导包括基因检测在内的诊断工作。
To describe chronological electrographic features of the interictal EEG background observed in two patients with MMPEI from neonatal to early infantile period. EEGs of two patients who fulfilled diagnostic criteria for MMPEI were acquired over the period of 6 months to monitor treatment efficacy and characterize seizures and other paroxysmal events. Both patients followed a similar sequential pattern. A distinctive evolution from a dysmature term neonatal EEG pattern to an asynchronous suppression burst pattern was observed prior to the interictal background becoming continuous. Physicians providing care to infants with intractable epilepsy and burst suppression EEG pattern should be alert to the possibility of MMPEI. An earlier diagnosis of MMPEI would help guide diagnostic workup including genetic testing.