The Use of Bioelectric Dressings in Skin Graft Harvest Sites: A Prospective Case Series
The Use of Bioelectric Dressings in Skin Graft Harvest Sites: A Prospective Case Series
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DOI：
10.1097/bcr.0b013e31823356e4
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发表时间：
2012-05-01
影响因子：
1.4
通讯作者：
Wilcox, Richard
中科院分区：
文献类型：
--
作者：
Blount, Andrew L.;Foster, Sarah;Wilcox, Richard
尽管在用于管理急性和慢性伤口的伤口护理治疗方面取得了进展，但对于加速上皮形成的干预仍然存在未满足的需求。过去许多作者都主张使用电流来加速伤口愈合。具有固有电活性的新型伤口敷料正在出现，并且缺乏对这些特定模式的研究。本研究的主要目的是评价生物电敷料对急性伤口愈合的影响。13例接受皮肤移植的患者入组。一半的皮肤移植供体部位使用生物电敷料和半封闭敷料（SOD）治疗，另一半仅使用SOD。上皮化由盲烧伤外科主治医师评定。参与者还提供了他们疤痕外观的自我评估。术后1周，生物电敷料治疗侧的平均上皮化率为71.8%，SOD侧为46.9%，伤口愈合平均快34.62%（P = 0.015）。1个月时，患者将生物电敷料治疗的一半在疤痕颜色（P = .198）、硬度（P = .088）、厚度（P = .038）和总体质量（P = .028）方面评为上级。这些早期数据表明，在急性伤口上使用生物电敷料，有望实现更快愈合、改善瘢痕形成和改善患者主观结局。随着扩展研究人群的完成，作者希望为将其数据外推到皮肤移植供体部位以外的所有伤口护理领域提供坚实的基础。（J Burn Care Res 2012;33：354-357）
Despite advances in wound care treatments for the management of acute and chronic wounds, there remains an unmet need for interventions that accelerate epithelialization. Many authors in the past have advocated the use of electric currents to accelerate wound healing. Novel wound dressings with inherent electric activity are emerging, and studies of these specific modalities are lacking. The principal aim of this study is to evaluate the impact of a bioelectric dressing on acute wound healing. Thirteen patients who underwent skin grafting were enrolled. One half of all skin graft donor sites were treated with the bioelectric dressing and semi-occlusive dressing (SOD) and the other half using solely a SOD. Epithelialization was rated by a blinded burn surgeon attending. Participants also provided a self-assessment of their scar appearance. At week 1 postprocedure, average epithelialization of 71.8% was noted on the bioelectric dressing-treated side, compared with 46.9% on the SOD side, representing an average 34.62% faster wound healing (P = .015). At 1 month, patients rated the bioelectric dressing-treated half as superior in terms of scar color (P = .198), stiffness (P = .088), thickness (P = .038), and overall quality (P = .028). These early data show promise in terms of faster healing, improved scarring, and improved patient subjective outcome with the use of the bioelectric dressing on acute wounds. With fulfillment of an extended study population, the authors hope to provide a solid foundation for extrapolating their data beyond skin graft donor sites to all areas of wound care. (J Burn Care Res 2012;33:354-357)