The effects of limitation of acitivity upon the human body.
The effects of limitation of acitivity upon the human body.
复制标题
限制活动对人体的影响。
DOI：
10.1001/jama.1966.03100230069017
复制
发表时间：
1966
期刊：
影响因子：
--
通讯作者：
F. Kottke
中科院分区：
文献类型：
--
作者：
F. Kottke
任何器官的功能在生理限度内取决于其活动的强度和频率。虽然休息可能对受损的器官有保护作用，但它会导致正常器官功能的逐渐丧失。长时间卧床休息时活动受限会导致多器官系统严重恶化，包括骨骼、神经肌肉、心血管、呼吸、泌尿生殖和神经系统。肌肉的完全不活动导致每天大约3%的力量损失。神经肌肉和情绪控制以及智力表现都因长时间卧床休息而受损。卧床休息时心血管功能下降的速度比恢复活动时更快。可能需要数年的时间来恢复骨骼在固定期间流失的钙。
The functional capacity of any organ is dependent within physiological limits upon the intensity and frequency of its activity. Although rest may be protective for a damaged organ it results in progressive loss of functional capacity for normal organs. Limitation of activity during prolonged bed rest causes significant deterioration of multiple organ systems including the skeletal, neuromuscular, cardiovascular, respiratory, urogenital, and nervous systems. Total inactivity of muscle results in loss of strength of approximately 3% per day. Neuromuscular and emotional control and intellectual performance are all impaired by prolonged bed rest. Cardiovascular function decreases during bed rest more rapidly than it is restored when activity is resumed. Years may be required to restore the calcium lost from the skeleton during immobilization.