Preliminary study of the association of white-matter metabolite concentrations with disease severity in patients with Huntington's disease.

Preliminary study of the association of white-matter metabolite concentrations with disease severity in patients with Huntington's disease.
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亨廷顿病患者白质代谢物浓度与疾病严重程度关系的初步研究。

DOI:
10.1176/appi.neuropsych.13020040
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发表时间:
2014
期刊:
The Journal of neuropsychiatry and clinical neurosciences
影响因子:
--
通讯作者:
Beglinger,LeighJ
Beglinger,LeighJ
中科院分区:
--
文献类型:
--
作者:
Yager,JeffreyR;Gasparovic,Charles;Magnotta,VincentA;Adams,William;Fiedorowicz,Jess;Paulsen,Jane;Jorge,Ricardo;Beglinger,LeighJ

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Proton magnetic resonance spectroscopy is used to measure several metabolites in cortical gray and white matter in patients with Huntington’s disease. The preliminary results show that CAG-repeat length correlates with white-matter N-acetylaspartate concentrations, and disease severity correlates with several metabolites.
DOI: 10.1002/mrm.22060
发表时间: 2009-09-01
影响因子: 3.3
作者:
Gasparovic, C.;Neeb, H.;Shah, N. J.
通讯作者: Shah, N. J.