Predictors of impact of vaginal symptoms in postmenopausal women.
Predictors of impact of vaginal symptoms in postmenopausal women.
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DOI：
10.1097/gme.0000000000000482
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发表时间：
2016-01
期刊：
影响因子：
--
通讯作者：
Huang AJ
中科院分区：
文献类型：
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作者：
Hunter MM;Nakagawa S;Van Den Eeden SK;Kuppermann M;Huang AJ
确定绝经后妇女阴道症状对功能和健康影响更大的相关因素。报告阴道干燥、瘙痒、刺激或性活动疼痛的绝经后女性完成了多维度的阴道老化日常影响（DIVA）问卷，并对可能影响阴道症状影响的多种社会人口统计学和临床因素进行了评估。多变量线性回归分析研究了选定的参与者特征和DIVA量表评分之间的关系，评估症状对日常生活活动，情绪健康，自我概念/身体形象和性功能的影响。在745名有症状的参与者中，平均年龄为56（±9）岁，66%为少数种族/民族。患有共病抑郁症的女性报告阴道症状对DIVA测量的功能和幸福感的所有维度的影响更大（医院和焦虑抑郁量表评分每增加3分，影响评分估计增加11%-22%）。患有尿失禁的女性还报告称，阴道症状对日常生活活动、情感健康和自我概念/身体形象的影响更大（估计影响评分增加27%-37%）。年龄、伴侣状况、性活动频率、总体健康状况和体重指数也预测了至少一个领域的更大影响。研究结果表明，应特别努力，以确定和治疗绝经后妇女的阴道症状已知有抑郁症或尿失禁，因为这些妇女可能会遇到更大的影响阴道症状的多个领域的功能和生活质量。
To identify factors associated with greater impact of vaginal symptoms on functioning and well-being in postmenopausal women. Postmenopausal women who reported vaginal dryness, itching, irritation, or pain with sexual activity completed the multidimensional Day-to-day Impact of Vaginal Aging (DIVA) questionnaire and underwent assessment of multiple socio-demographic and clinical factors having the potential to influence the impact of vaginal symptoms. Multivariable linear regression analyses examined relationships between selected participant characteristics and DIVA scale scores assessing symptom impact on activities of daily living, emotional well-being, self-concept/body image, and sexual functioning. Among the 745 symptomatic participants, mean age was 56 (±9) years, and 66% were racial/ethnic minorities. Women with comorbid depression reported greater impact of vaginal symptoms on all dimensions of functioning and well-being measured by DIVA (11%–22% estimated increase in impact scores associated with each 3-point increase in Hospital and Anxiety Depression Scale scores). Women with urinary incontinence also reported greater impact of vaginal symptoms on activities of daily living, emotional well-being, and self-concept/body image (27%–37% estimated increase in impact scores). Age, partner status, sexual activity frequency, general health, and body mass index also predicted greater impact in at least one domain. Findings suggest that special efforts should be made to identify and treat vaginal symptoms in postmenopausal women known to have depression or urinary incontinence, as these women may experience greater impact of vaginal symptoms on multiple domains of functioning and quality of life.