Development of proton CT imaging system using plastic scintillator and CCD camera
Development of proton CT imaging system using plastic scintillator and CCD camera
复制标题
使用塑料闪烁体和CCD相机开发质子CT成像系统
DOI：
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发表时间：
2016
影响因子：
3.5
通讯作者：
M. Uesaka
中科院分区：
文献类型：
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作者：
Sodai Tanaka;T. Nishio;K. Matsushita;M. Tsuneda;S. Kabuki;M. Uesaka
建立了质子计算机断层扫描（pCT）成像系统，用于评估x射线CT （xCT）到wel（水当量长度）转换在质子治疗计划中的误差。在该系统中，利用CCD相机摄影获得沿光束方向集成的闪烁光，使数据采集快速方便。使用事先制作的光-距离转换表将光强度转换为质子束的范围，并重建pCT图像。利用国家放射科学研究所的AVF930回旋加速器提供的70 MeV质子束进行了pCT系统演示实验。根据实验数据重建三维pCT图像。清晰地观察到约1 mm的薄结构，pCT图像的空间分辨率与xCT图像相同。对不同物质的pCT图像进行重构，评估pCT图像的像素值。对包括多重库仑散射在内的图像质量劣化进行了研究。
A proton computed tomography (pCT) imaging system was constructed for evaluation of the error of an x-ray CT (xCT)-to-WEL (water-equivalent length) conversion in treatment planning for proton therapy. In this system, the scintillation light integrated along the beam direction is obtained by photography using the CCD camera, which enables fast and easy data acquisition. The light intensity is converted to the range of the proton beam using a light-to-range conversion table made beforehand, and a pCT image is reconstructed. An experiment for demonstration of the pCT system was performed using a 70 MeV proton beam provided by the AVF930 cyclotron at the National Institute of Radiological Sciences. Three-dimensional pCT images were reconstructed from the experimental data. A thin structure of approximately 1 mm was clearly observed, with spatial resolution of pCT images at the same level as that of xCT images. The pCT images of various substances were reconstructed to evaluate the pixel value of pCT images. The image quality was investigated with regard to deterioration including multiple Coulomb scattering.