Prostate biopsy culture findings of men with chronic pelvic pain syndrome do not differ from those of healthy controls
Prostate biopsy culture findings of men with chronic pelvic pain syndrome do not differ from those of healthy controls
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DOI：
10.1016/s0022-5347(05)63958-4
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发表时间：
2003-02-01
影响因子：
6.6
通讯作者：
Berger, RE
中科院分区：
文献类型：
--
作者：
Lee, JC;Muller, CH;Berger, RE
目的：之前的报告已经确定了患有慢性盆腔疼痛综合征的男性前列腺中的细菌。为了检查慢性盆腔疼痛综合征患者中前列腺细菌是否比无盆腔疼痛的患者更普遍，我们比较了 4 杯尿检和前列腺活检结果。 材料和方法：总共 120 名 IIIa 型和 IIIb 型慢性盆腔疼痛综合征患者和 60 名无症状对照者接受了标准 4 杯尿检，通过血细胞计数器和经会阴数字引导前列腺检查表达的前列腺分泌白细胞活检。对组织进行需氧菌、厌氧菌、阴道毛滴虫、沙眼衣原体和单纯疱疹病毒培养。对一部分患者和对照进行皮肤培养。结果：从患者和对照中获得阳性前列腺活检培养。在 118 名疼痛患者中的 45 名 (38%) 和 59 名对照者中的 21 名 (36%) 中发现了细菌 (p = 0.74)。年长的男性更有可能拥有积极的文化。患有 IIIa 型慢性盆腔疼痛综合征的男性比患有 IIIb 型慢性盆腔疼痛综合征的男性更有可能前列腺活检培养物呈阳性。结论：经会阴前列腺活检培养的细菌在患有和不患有慢性盆腔疼痛综合征的男性之间没有差异。通过活检获得的前列腺细菌在病因学上可能与大多数患有慢性盆腔疼痛综合征的男性的症状无关。
Purpose: Previous reports have identified bacteria in the prostate of men with chronic pelvic pain syndrome. To examine whether prostatic bacteria are more prevalent among patients with chronic pelvic pain syndrome than among those without pelvic pain, we compared 4-glass urine test and prostate biopsy results.Materials and Methods: A total of 120 patients with types IIIa and IIIb chronic pelvic pain syndrome and 60 asymptomatic controls underwent a standard 4-glass urine test, examination of expressed prostatic secretion leukocytes by hemocytometer and transperineal, digitally guided prostate biopsies. Tissue was cultured for aerobes, anaerobes, Trichomonas vaginalis, Chlamydia trachomatis and herpes simplex virus. Skin cultures were performed on a subset of patients and controls.Results: Positive prostate biopsy cultures were obtained from patients and controls. Bacteria were found in 45 of 118 pain patients (38%) and in 21 of 59 controls (36%) (p = 0.74). Older men were more likely to have positive cultures. Men with type IIIa chronic pelvic pain syndrome were more likely than those with type IIIb to have positive prostate biopsy cultures.Conclusions: Bacteria cultured from transperineal prostatic biopsies do not differ between men with and without chronic pelvic pain syndrome. Prostatic bacteria obtained by biopsy are probably not etiologically related to the symptoms in the majority of men with chronic pelvic pain syndrome.