Morphological and statistical investigation of the occurrence of 'tubule-like cells' in the renal corpuscle of the mouse kidney induced by sex hormones.

Morphological and statistical investigation of the occurrence of 'tubule-like cells' in the renal corpuscle of the mouse kidney induced by sex hormones.
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性激素诱导的小鼠肾肾小体中“肾小管样细胞”发生的形态学和统计研究。

DOI:
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发表时间:
1984
期刊:
Renal Physiology
影响因子:
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通讯作者:
M. Melis
M. Melis
中科院分区:
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文献类型:
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作者:
F. Barberini;G. Familiari;I. Vittori;F. Carpino;M. Melis

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在这篇报告中,作者描述了构成小鼠肾脏鲍曼氏囊壁层的一些细胞的结构和超微结构特征,这些细胞与近曲小管的上皮细胞(肾小管样细胞)非常相似。这些元素在成熟和未成熟的两性小鼠中均可见,但它们的精细形态和统计发生率似乎与小鼠的性别和年龄有关,正如相同动物对实验性激素的不同反应所揭示的那样。这些物质直接和/或通过影响促性腺激素(尤其是促黄体激素)能够改变(主要是增加)具有肾小管样细胞的肾小体的百分比。
In this report the authors describe the structural and ultrastructural characteristics of some cells constituting the parietal layer of Bowman's capsule of the mouse kidney, which are very similar to the epithelial cells of the proximal convoluted tubule (tubule-like cells). These elements are noted in mature and immature mice of both sexes, but their fine morphology and statistical incidence seem related to the sex and the age of the mice, as revealed by the different responsiveness of the same animals to sex hormones experimentally administered. Such substances, directly and/or through an influence on gonadotropins (especially luteinizing hormone), are able to modify (mainly increasing) the percentage of renal corpuscles possessing tubule-like cells.