Neuronal Modulation of Auditory Attention by Informative and Uninformative Spatial Cues
Neuronal Modulation of Auditory Attention by Informative and Uninformative Spatial Cues
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DOI：
10.1002/hbm.20631
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发表时间：
2009-05-01
影响因子：
4.8
通讯作者：
Harrington, Deborah L.
中科院分区：
文献类型：
--
作者：
Mayer, Andrew R.;Franco, Alexandre R.;Harrington, Deborah L.
声音提供了关于空间环境的重要信息，包括接近物体的位置。对声音的注意力可以通过自动或更多的控制过程来引导，这在视觉模态中已经得到了很好的研究。然而，人们对听觉信号的注意控制机制的神经基础知之甚少。我们研究了健康的成年人，他们在执行一项任务时接受了事件相关的FMRI，通过改变线索正确预测目标位置的概率来操纵自动和更受控制的听觉定向。具体来说，我们研究了非信息性（50%效度）和信息性（75%效度）听觉线索对反应时间（RT）和神经元功能的影响。线索和目标之间的刺激启动异步（SOA）为100或800毫秒。在100毫秒的SOA中，两种线索类型的有效RT都比无效RT快，无效的额顶叶激活比有效的额顶叶激活更大。在800毫秒的SOA中，RT和功能激活取决于线索是提供信息还是不提供信息，以及线索对目标位置的预测是正确还是错误。与我们的预测相反，在几个不同的比较和两个soa中，额顶叶网络的激活对于非信息性线索比信息性线索更大。这一发现与类似的视觉定向研究形成了对比，并表明听觉模式可能更倾向于在无信息提示下自动转移注意力。中国生物医学工程学报（英文版），2009。(C) 2008 Wiley-Liss, Inc。
Sounds provide important information about the spatial environment, including the location of approaching objects. Attention to sounds can be directed through automatic or more controlled processes, which have been well studied in the visual modality. However, little is known about the neural underpinnings of attentional control mechanisms for auditory signals. We studied healthy adults who underwent event-related FMRI while performing a task that manipulated automatic and more controlled auditory orienting by varying the probability that cues correctly predicted target location. Specifically, we examined the effects of uninformative (50% validity ratio) and informative (75% validity ratio) auditory cues on reaction time (RT) and neuronal functioning. The stimulus-onset asynchrony (SOA) between the cue and the target was either 100 or 800 ms. At the 100 ms SOA, RT was faster for valid than invalid trials for both cue types, and frontoparietal activation was greater for invalid than valid trials. At the 800 ms SOA, RT and functional activation depended on whether cues were informative or uninformative, and whether cues correctly or incorrectly predicted the target location. Contrary to our prediction, activation in a frontoparietal network was greater for uninformative than informative cues across several different comparisons and at both SOAs. This finding contrasts with similar research of visual orienting, and suggests that the auditory modality may be more biased toward automatic shifts of attention following uninformative cues. Hum Brain Mapp 30:1652-1666, 2009. (C) 2008 Wiley-Liss, Inc.