Detection of bladder carcinoma in females by flow cytometry and cytology.
Detection of bladder carcinoma in females by flow cytometry and cytology.
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通过流式细胞术和细胞学检测女性膀胱癌。
DOI：
10.1002/cyto.990100611
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Melamed,MR
中科院分区：
文献类型：
--
作者：
Hermansen,DK;Badalament,RA;Fair,WR;Kimmel,M;WhitmoreJr,WF;Melamed,MR
对1985年6月至1986年12月期间在纪念斯隆-凯特琳癌症中心接受膀胱癌评价的所有女性进行膀胱冲洗流式细胞术（BWFCM）、排尿细胞学（VUC）和膀胱镜检查（CUC）时获得的导尿管尿液细胞学的灵敏度进行了审查。这包括48名女性中64例经病理证实的膀胱癌。综合考虑阳性和可疑结果，BWFCM、CUC和3VUC的敏感性分别为75%、64%和56%。如果只考虑阳性结果（即，BWFCM、CUC和3VUC的敏感性分别为64%、31%和32%。这些试验的敏感性低于主要为男性的人群，可能与鳞状上皮的存在和更高频率的脓尿有关。然而，膀胱冲洗流式细胞术和常规细胞学仍然是一个非常有价值的膀胱镜检查，BWFCM与常规细胞学的组合是更敏感的比单独的程序。
The sensitivity of bladder wash flow cytometry (BWFCM), voided urinary cytology (VUC), and cytology of cathetrized urine obtained at the time of cystoscopy (CUC) were reviewed on all women evaluated for bladder cancer at Memorial Sloan‐Kettering Cancer Center between June 1985 and December 1986. This comprised sixty‐four episodes of pathologically proven bladder cancer in 48 women. Considering positive and suspicious results jointly the sensitivities of BWFCM, CUC and 3 VUC were 75%, 64% and 56%, respectively. If only positive results were considered (i.e., suspicious results considered as negative), the sensitivities of BWFCM, CUC and 3 VUC were 64%, 31% and 32%, respectively. The sensitivities of these tests are less than for a predominantly male population, presumably related to the presence of squamous epithelium and greater frequency of pyuria. However, bladder wash flow cytometry and conventional cytology are still a very valuable addition to cystoscopic examination, and the combination of BWFCM with conventional cytology is more sensitive than either procedure alone.