11C-Acetate and 18F-FDG PET/CT for Clinical Staging and Selection of Patients with Hepatocellular Carcinoma for Liver Transplantation on the Basis of Milan Criteria: Surgeon's Perspective
11C-Acetate and 18F-FDG PET/CT for Clinical Staging and Selection of Patients with Hepatocellular Carcinoma for Liver Transplantation on the Basis of Milan Criteria: Surgeon's Perspective
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DOI：
10.2967/jnumed.112.107516
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发表时间：
2013-02-01
影响因子：
9.3
通讯作者：
Fan, Sheung Tat
中科院分区：
文献类型：
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作者：
Cheung, Tan To;Ho, Chi Lai;Fan, Sheung Tat
肝细胞癌(肝细胞癌)肝移植(LT)的成功率通过根据米兰标准仔细选择患者而得到提高。这些标准传统上是通过对比CT来评估的，众所周知，增强CT会受到肝硬变结构或构筑变化的影响。我们的目的是在米兰标准的基础上比较双示踪剂(C-11-乙酸酯和F-18-FDG)PET/CT和增强CT在患者选择方面的作用。方法：对手术前1个月内行双示踪PET/CT和增强CT检查的肝细胞癌患者进行回顾性研究。然后，他们接受了肝移植(n=22)或肝部分切除术(n=21；
The success of liver transplantation (LT) for hepatocellular carcinoma (HCC) is enhanced by careful patient selection on the basis of the Milan criteria. The criteria are traditionally assessed by contrast CT, which is known to be affected by structural or architectural changes in cirrhotic livers. We aimed to compare dual-tracer (C-11-acetate and F-18-FDG) PET/CT with contrast CT for patient selection on the basis of the Milan criteria. Methods: Patients who had HCC and had undergone both preoperative dual-tracer PET/CT and contrast CT within a 1-mo interval were retrospectively studied. They then underwent either LT (n = 22) or partial hepatectomy (PH) (n = 21; HCC of