COLUMNAR ORGANIZATION OF CORTICOCORTICAL PROJECTIONS IN SQUIRREL AND RHESUS-MONKEYS - SIMILARITY OF COLUMN WIDTH IN SPECIES DIFFERING IN CORTICAL VOLUME
COLUMNAR ORGANIZATION OF CORTICOCORTICAL PROJECTIONS IN SQUIRREL AND RHESUS-MONKEYS - SIMILARITY OF COLUMN WIDTH IN SPECIES DIFFERING IN CORTICAL VOLUME
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DOI：
10.1002/cne.902200309
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发表时间：
1983-01-01
影响因子：
2.5
通讯作者：
GOLDMANRAKIC, PS
中科院分区：
文献类型：
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作者：
BUGBEE, NM;GOLDMANRAKIC, PS
为了比较2种不同脑容量的灵长类动物皮质-皮质投影末端分布的大小和模式，在新世界松鼠猴（S. sciureus）和旧世界恒河猴（M. mulatta）的前额叶皮层注射了氚化氨基酸，并对它们的大脑进行了光显微放射自显影。在这两种动物中，前额叶传出信号被定向到相同和相反半球的许多皮层目标，在冠状面切片中，它们通常以径向定向柱终止。在恒河猴中，横切面柱的中间宽度为685 μ m。在松鼠猴中，相应的列的中位数宽度为555 μ m。考虑到恒河猴的新皮层体积约为。4.5的同学们。松鼠猴和松鼠猴的皮质柱比松鼠猴大，但它们的皮质柱尺寸惊人地相似。这一发现表明，皮层表面积的系统发育扩张伴随着传入纤维柱数量的增加，而不是宽度的增加。模块化单元数量的增加可能与进化过程中大脑皮层计算和信息处理能力的增强有关。
To compare the size and pattern of the terminal distribution of cortico-cortical projections in 2 primate species with brains of different size, tritiated amino acids were injected into the prefrontal cortex of New World squirrel monkeys (S. sciureus) and Old World rhesus monkeys (M. mulatta), and their brains were processed for light microscopic autoradiography. In both species, prefrontal efferents are directed to a number of cortical targets in the same and opposite hemispheres, where in coronal sections, they generally terminate as radially oriented columns. In the rhesus monkey, the median width of the columns in transverse sections in 685 .mu.m. In squirrel monkey, corresponding columns have a median width of 555 .mu.m. Considering that the volume of the neocortex in rhesus monkey is .apprx. 4.5 .times. larger than that of squirrel monkey, the dimensions of cortical columns in the 2 species are surprisingly similar. This finding suggests that phylogenetic expansion in cortical surface area is accompanied by an increase in the number, rather than the width, of afferent fiber columns. The increase in number of modular units may be relevant to the increasing computational and information processing capacity of the cerebral cortex in the course of evolution.