Review of clinical experience with ion beam radiotherapy

Review of clinical experience with ion beam radiotherapy
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DOI:
10.1259/bjr/71511359
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发表时间:
2011-12-01
影响因子:
2.6
通讯作者:
Debus, J.
Debus, J.
中科院分区:
医学3区
文献类型:
--
作者:
Jensen, A. D.;Muenter, M. W.;Debus, J.

文献摘要

被引文献

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这篇文章描述了海德堡大学医院肿瘤学作为核心学科的早期发展,以及离子束治疗的第一步,从与达姆施塔特Schwerionenforschung Gesellschaft合作开展的试点项目到海德堡重离子中心(HIT)临床服务的初步启动。我们根据文献中发表的数据,概述了有关使用离子束治疗活性粒子中心主要适应症的现有临床证据。给出了在这些适应症中使用粒子治疗的基本原理。鉴于资料有限,我们讨论进行临床试验的必要性。我们也期待着将在哈工大开展的下一步活动。
The article describes both the early development of oncology as a core discipline at the University of Heidelberg Hospital and the first steps towards ion beam treatment, from the pilot project carried out in co-operation with the Gesellschaft fur Schwerionenforschung Darmstadt to the initial start-up of clinical service at the Heidelberg Heavy Ion Centre (HIT). We present an overview, based on data published in the literature, of the available clinical evidence relating the use of ion beam therapy to treat major indications in active particle centres. A rationale for the use of particle therapy in each of these indications is given. In view of the limited availability of data, we discuss the necessity to conduct clinical trials. We also look forward towards the next activities to be undertaken at the HIT.