Structures Unveil the Invasion Mechanism of Chikungunya Virus
Structures Unveil the Invasion Mechanism of Chikungunya Virus
复制标题
结构揭示基孔肯雅病毒的入侵机制
DOI：
10.1016/j.tim.2019.05.011
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发表时间：
2019
影响因子：
15.9
通讯作者：
Cheng Wei
中科院分区：
文献类型：
--
作者：
Sun Qiu;Du Xiao;Cheng Wei
多种致关节炎甲病毒受体MXRA 8以及与基孔肯雅病毒复合的MXRA 8的结构（Songet al.，Cell，2019; Basoreet al.，Cell，2019）揭示了病毒入侵的潜在机制，并可能促进新型疫苗和进入抑制剂的开发。
Structures of the multiple arthritogenic alphavirus receptor MXRA8 as well as MXRA8 in complex with chikungunya virus (Songet al.,Cell, 2019; Basoreet al.,Cell, 2019) have revealed the mechanism underlying viral invasion and could facilitate the development of novel vaccines and entry inhibitors.