Defective renal water excretion in nephrotic syndrome: the relationship between renal water excretion and kidney function, arginine vasopressin, angiotensin II and aldosterone in plasma before and after oral water loading

Defective renal water excretion in nephrotic syndrome: the relationship between renal water excretion and kidney function, arginine vasopressin, angiotensin II and aldosterone in plasma before and after oral water loading
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肾病综合征肾水排泄缺陷:口服水负荷前后肾水排泄与肾功能、血浆精氨酸加压素、血管紧张素II、醛固酮的关系

DOI:
10.1111/j.1365-2362.1985.tb00139.x
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发表时间:
1985
影响因子:
5.5
通讯作者:
T. Jensen
T. Jensen
中科院分区:
医学3区
文献类型:
--
作者:
E. Pedersen;H. Danielsen;M. Madsen;T. Jensen

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抽象的。对17名肾病综合征患者和15名健康对照受试者给予20 ml(kg体重)-1的口服水负荷。分别于负荷前及负荷后4 h内测定3次利尿(D)、游离水清除率(CH 2 O)、血浆精氨酸加压素(AVP)、血管紧张素II(AII)和醛固酮(Aldo)浓度。在肾病综合征中,D在负荷后1-2小时显著低于对照受试者,主要是由于较低的CH 2 O(2.61和7.01 ml min-1(中位数),P <0.01)。
Abstract. An oral water load of 20 ml (kg body wt)‐1 was given to seventeen patients with the nephrotic syndrome and fifteen healthy control subjects. Diuresis (D), free water clearance (CH2O), plasma concentrations of arginine vasopressin (AVP), angiotensin II (AII) and aldosterone (Aldo) were determined before and 3 times during the first 4 h after loading. In the nephrotic syndrome D was significantly lower 1–2 h after loading than in the control subjects, predominantly due to a lower CH2O (2·61 and 7·01 ml min‐1 (medians), P < 0·01).
大鼠慢性血清病肾功能与免疫病理学的关系。
DOI: 10.1038/ki.1983.140
发表时间: 1983
影响因子: 19.6
作者:
VanLiew,JB;Brentjens,JR;Noble,B
通讯作者: Noble,B