Addressable high-information-density DNA nanostructures
Addressable high-information-density DNA nanostructures
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DOI：
10.1016/j.cplett.2007.04.018
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发表时间：
2007-05-25
影响因子：
2.8
通讯作者：
Norden, Bengt
中科院分区：
文献类型：
--
作者：
Tumpane, John;Sandin, Peter;Norden, Bengt
我们提出了一种自组装迄今为止报道的最小 DNA 纳米结构的策略，这些纳米结构也可以根据 DNA 碱基代码进行寻址。使用线性以及新颖的分支三向DNA、寡核苷酸构建块，我们演示了纳米网络基本单元的形成，即边长为4 nm的DNA伪六边形。该网络固有的可寻址性将允许以亚纳米精度进行功能化，从而产生前所未有的丰富信息密度，这在摩尔定律和纳米芯片技术的背景下非常重要。 (c) 2007 年 Elsevier B.V. 出版
We present a strategy for self-assembly of the smallest yet reported DNA nanostructures that are also addressable in terms of their DNA-base code. Using linear as well as novel branched three-way DNA., oligonucleotide building-blocks we demonstrate the formation of a nano-network's fundamental cell, a DNA pseudo-hexagon of side 4 nm. The network's inherent addressability will allow functionalization with sub-nanometer precision yielding unprecedented richness in information density, important in the context of Moore's Law and nano-chip technology. (c) 2007 Published by Elsevier B.V.