A BENDING ENERGY-MODEL FOR MEASUREMENT OF CARDIAC SHAPE DEFORMITY

A BENDING ENERGY-MODEL FOR MEASUREMENT OF CARDIAC SHAPE DEFORMITY
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DOI:
10.1109/42.97580
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发表时间:
1991-09-01
影响因子:
10.6
通讯作者:
ZARET, BL
ZARET, BL
中科院分区:
工程技术1区
文献类型:
--
作者:
DUNCAN, JS;LEE, FA;ZARET, BL

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描述了一种分析和量化心脏左心室(LV)的内膜轮廓的形状特征的方法。 该方法适用于从几种成像模式中的任何一种获得的轮廓数据,并且涉及将任何特定轮廓建模为薄的柔性杆,其未变形状态由对一组正常受试者进行的测量来定义。 计算开始于在100个等距点中的每一个处找到所考虑的轮廓与平均正常轮廓之间的局部曲率差。 这些差异的加权平方,总结了一组点,被证明是区域或全球的弯曲能量变形的平均正常轮廓的特征形状的分析轮廓。 恢复,平滑和曲率计算的问题被认为是用于分析中使用的图像衍生的数字轮廓。 对人工轮廓数据和来自人类对比心室造影(CV)研究的数据进行实验。 它也表明,该方法已被改编为平衡放射性核素心血管造影(ERNA)测量内皮细胞的形状。 据称,该方法为任何特定的LV内膜轮廓的形状畸形提供了清晰的视觉定量评估。
An approach to analyzing and quantifying the shape characteristics of the endocardial contour of the left ventricle (LV) of the heart is described. The method is adaptable to contour data derived from any one of several imaging modalities and involves modeling any particular contour as a thin flexible rod, whose undeformed state is defined by measurements made on a group of normal subjects. The computation begins by finding the local curvature differences between the contour under consideration and the mean normal contour at each of 100 equidistant points. The weighted square of these differences, summed over a set of points, is shown to be the regional or global bending energy required to deform the mean normal contour to the characteristic shape of the analyzed contour. Resampling, smoothing and curvature computation issues are considered for the image-derived digital contours that are used in the analysis. Experiments were performed on artificial contour data and data derived from contrast ventriculographic (CV) studies of humans. It is also shown that the method has been adapted to measure endocardial shape from equilibrium radionuclide angiocardiography (ERNA). It is claimed that the approach provides a clear visual quantitative assessment of shape deformity for any particular LV endocardial contour.