The functioning and well-being of depressed patients. Results from the Medical Outcomes Study.
The functioning and well-being of depressed patients. Results from the Medical Outcomes Study.
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DOI：
10.1001/jama.1989.03430070062031
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发表时间：
1989-08
期刊：
影响因子：
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通讯作者：
K. Wells;A. Stewart;Ron D. Hays;M. Burnam;W. Rogers;M. Daniels;S. Berry;S. Greenfield;J. Ware-J.
中科院分区：
文献类型：
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作者：
K. Wells;A. Stewart;Ron D. Hays;M. Burnam;W. Rogers;M. Daniels;S. Berry;S. Greenfield;J. Ware-J.
我们描述了抑郁症患者相对于患有慢性疾病或无慢性疾病患者的身体机能和健康状况。数据来自美国三个地区的三个医疗服务系统中的11242名门诊患者。与无慢性疾病的患者相比，患有当前抑郁症或无抑郁症但有抑郁症状的患者往往身体机能、社交能力和角色功能更差，对自身当前健康状况的感知更差，身体疼痛更严重。无论是否患有抑郁症，与抑郁症状独特相关的身体机能差的情况，与八种主要慢性疾病独特相关的情况相当，甚至更糟。例如，因抑郁症状卧床的天数的独特关联显著大于与高血压、糖尿病和关节炎相关的可比关联。抑郁症和慢性疾病对患者的身体机能有独特的和累加的影响。
We describe the functioning and well-being of patients with depression, relative to patients with chronic medical conditions or no chronic conditions. Data are from 11,242 outpatients in three health care provision systems in three US sites. Patients with either current depressive disorder or depressive symptoms in the absence of disorder tended to have worse physical, social, and role functioning, worse perceived current health, and greater bodily pain than did patients with no chronic conditions. The poor functioning uniquely associated with depressive symptoms, with or without depressive disorder, was comparable with or worse than that uniquely associated with eight major chronic medical conditions. For example, the unique association of days in bed with depressive symptoms was significantly greater than the comparable association with hypertension, diabetes, and arthritis. Depression and chronic medical conditions had unique and additive effects on patient functioning.